Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17613666 | 0.82 | TSHR (0.39) | TSHRMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL17613728 | 0.78 | — | — | |
| SCHEMBL17613686 | 0.76 | DNM1 (0.34) | TSHRMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL17613698 | 0.75 | TSHR (0.43) | TSHRMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL17613692 | 0.73 | TSHR (0.36) | TSHRMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL17613731 | 0.72 | THRA (0.31) | KDM4ESMN1; SMN2 | |
| SCHEMBL17613610 | 0.68 | ALDH1A1 (0.31) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL17613689 | 0.67 | KDM4E (0.35) | KDM4ESMN1; SMN2GAA | |
| Di(Hydroxyethyl)Ether SCHEMBL11310542 | 0.67 | TSHR (0.77) | TSHRMAPK1MEN1KMT2AGAA | |
| Di(Hydroxyethyl)Ether SCHEMBL28993299 | 0.67 | TSHR (0.77) | TSHRMAPK1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346883-B1 | SELF DELIVERING BIO-LABILE PHOSPHATE PROTECTED PRO-OLIGOS FOR OLIGONUCLEOTIDE BASED THERAPEUTICS AND MEDIATING RNA INTERFERENCE | PETERSEN SCOTT G (US) | 2016-03-23 | — | — | EP | disclosed |