Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18005347 | 0.85 | CYP1A2 (0.44) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL15574022 | 0.84 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL25334623 | 0.78 | KDM4E (0.46) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL14782540 | 0.77 | LMNA (0.52) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL439716 | 0.74 | LMNA (0.59) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL423183 | 0.74 | PDE2A (0.61) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL20733647 | 0.74 | L3MBTL1 (0.52) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL401292 | 0.72 | LMNA (0.54) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL8656719 | 0.72 | LMNA (0.48) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL401293 | 0.72 | CYP1A2 (0.48) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994030-A | Preparation method of pyrimidine derivative 4, 6-dichloro-2-pyrimidine carboxylic acid methyl ester | 上海毕臣生化科技有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-118994030-A | Preparation method of pyrimidine derivative 4, 6-dichloro-2-pyrimidine carboxylic acid methyl ester | 上海毕臣生化科技有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2016044285-A1 | SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF PYRIDINE CARBOXYLIC ACID HERBICIDES AND ALS INHIBITORS | DOW AGROSCIENCES LLC (US) | 2016-03-24 | — | — | WO | disclosed |