Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176260 | 0.86 | GABRA1 (0.42) | GABRA1GABRB2KDM4EALDH1A1AKR1B1 | |
| SCHEMBL7395144 | 0.81 | GABRA1 (0.39) | GABRA1GABRB2KDM4EALDH1A1AKR1B1 | |
| SCHEMBL3661576 | 0.77 | GABRA1 (0.41) | GABRA1GABRB2KDM4EALDH1A1AKR1B1 | |
| SCHEMBL6805441 | 0.75 | GABRA1 (0.44) | GABRA1GABRB2KDM4EALDH1A1AKR1B1 | |
| SCHEMBL3267471 | 0.75 | THRB (0.37) | GABRA1GABRB2KDM4EALDH1A1 | |
| SCHEMBL7726842 | 0.74 | THRA (0.39) | GABRA1GABRB2 | |
| SCHEMBL1638775 | 0.73 | GABRA1 (0.50) | GABRA1GABRB2KDM4EALDH1A1AKR1B1 | |
| SCHEMBL4789832 | 0.73 | GABRA1 (0.41) | GABRA1GABRB2KDM4EALDH1A1AKR1B1 | |
| SCHEMBL7761703 | 0.73 | GABRA1 (0.41) | GABRA1GABRB2KDM4EALDH1A1AKR1B1 | |
| SCHEMBL5454296 | 0.73 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428973-A1 | Mixtures of stabilisers for elastomers | CIBA-GEIGY AG (CH) | 1991-05-29 | — | — | EP | disclosed |