Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.32 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631671 | 0.88 | USP30 (0.41) | DYRK1BCDK9 | |
| SCHEMBL17632095 | 0.88 | USP30 (0.41) | DYRK1BCDK9 | |
| SCHEMBL17631644 | 0.84 | CDK9 (0.40) | TBK1CDK9PRKD1PRKD2 | |
| SCHEMBL17632600 | 0.79 | CDK9 (0.39) | CDK9 | |
| SCHEMBL17631915 | 0.79 | CDK9 (0.35) | TBK1CDK9 | |
| SCHEMBL17631866 | 0.79 | CDK9 (0.41) | CDK9 | |
| SCHEMBL17632617 | 0.78 | CDK9 (0.42) | MKNK1MKNK2DYRK1BCDK9PRKD1 | |
| SCHEMBL17631858 | 0.78 | CDK9 (0.35) | TLR9TLR8TLR7CDK9 | |
| SCHEMBL17632111 | 0.77 | UCHL1 (0.35) | TLR9TLR8TLR7DYRK1BCDK9 | |
| SCHEMBL17631859 | 0.76 | USP30 (0.39) | MKNK1MKNK2ABL1TLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |