Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 7/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.36 |
| ▸ | PRKCI | P41743 | 3/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632095 | 0.85 | USP30 (0.41) | CDK9GSK3BUSP30 | |
| SCHEMBL17631671 | 0.85 | USP30 (0.41) | CDK9GSK3BUSP30 | |
| SCHEMBL17632283 | 0.84 | MKNK1 (0.38) | CDK9PRKD1PRKD2TBK1 | |
| SCHEMBL17632570 | 0.80 | USP30 (0.34) | CDK9PRKD1PRKD2PRKCIUSP30 | |
| SCHEMBL17631866 | 0.79 | CDK9 (0.41) | CDK9GSK3BPRKCI | |
| SCHEMBL17631915 | 0.79 | CDK9 (0.35) | CDK9TBK1 | |
| SCHEMBL17631858 | 0.78 | CDK9 (0.35) | CDK9 | |
| SCHEMBL17632111 | 0.77 | UCHL1 (0.35) | CDK9USP30 | |
| SCHEMBL17632600 | 0.77 | CDK9 (0.39) | CDK9 | |
| SCHEMBL17632617 | 0.76 | CDK9 (0.42) | CDK9GSK3BPRKD1PRKD2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |