Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 9/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631550 | 0.84 | ABL1 (0.41) | MAP4K1MAPTABL1ITK | |
| SCHEMBL17632020 | 0.82 | MAPT (0.46) | MAPTITK | |
| SCHEMBL17631887 | 0.81 | USP30 (0.44) | MAP4K1MAPTABL1KITPDGFRA | |
| SCHEMBL17632007 | 0.80 | LIPG (0.41) | MAP4K1ABL1PIK3CG | |
| SCHEMBL17632490 | 0.80 | MAPT (0.43) | MAPT | |
| SCHEMBL17632035 | 0.79 | ABL1 (0.45) | MAP4K1ABL1KITPDGFRA | |
| SCHEMBL17632611 | 0.77 | RAB9A (0.37) | MAPT | |
| SCHEMBL17632567 | 0.77 | BRD4 (0.47) | MAP4K1 | |
| SCHEMBL17631984 | 0.76 | DYRK1A (0.33) | MAP4K1MAPTITK | |
| SCHEMBL17632621 | 0.76 | ALDH1A1 (0.47) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |