Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632490 | 0.88 | MAPT (0.43) | DYRK1AALDH1A1MAPTTP53NPC1 | |
| SCHEMBL17632611 | 0.87 | RAB9A (0.37) | DYRK1AMAPTNPC1RAB9A | |
| SCHEMBL17632621 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTTP53NPC1RAB9A | |
| SCHEMBL17632229 | 0.84 | CYP2D6 (0.42) | DYRK1A | |
| SCHEMBL17632020 | 0.84 | MAPT (0.46) | DYRK1AALDH1A1MAPTTP53ITK | |
| SCHEMBL17632007 | 0.84 | LIPG (0.41) | ALDH1A1MAP4K1 | |
| SCHEMBL17631550 | 0.81 | ABL1 (0.41) | MAPTTP53MAP4K1ITK | |
| SCHEMBL17632035 | 0.81 | ABL1 (0.45) | MAP4K1 | |
| SCHEMBL17632567 | 0.79 | BRD4 (0.47) | ALDH1A1MAP4K1 | |
| SCHEMBL17631887 | 0.78 | USP30 (0.44) | MAPTMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |