Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 9/20 | 0.48 |
| ▸ | UCHL1 | P09936 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19260046 | 0.81 | USP30 (0.62) | CPB1USP30UCHL1KMT2AMEN1 | |
| SCHEMBL17631874 | 0.81 | USP30 (0.51) | USP30 | |
| SCHEMBL17632036 | 0.79 | USP30 (0.50) | USP30UCHL1 | |
| SCHEMBL17632621 | 0.78 | ALDH1A1 (0.47) | USP30KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL17632007 | 0.78 | LIPG (0.41) | ALDH1A1LMNAKDM4E | |
| SCHEMBL17631936 | 0.77 | USP30 (0.37) | USP30 | |
| SCHEMBL17632437 | 0.77 | USP30 (0.48) | USP30UCHL1NPC1RAB9A | |
| SCHEMBL17631671 | 0.76 | USP30 (0.41) | USP30 | |
| SCHEMBL17632095 | 0.76 | USP30 (0.41) | USP30 | |
| SCHEMBL17632381 | 0.75 | USP30 (0.48) | USP30UCHL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |