Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632261 | 0.87 | HPGDS (0.41) | USP30CDK9CHEK1KCNH2SLC6A2 | |
| SCHEMBL17631874 | 0.81 | USP30 (0.51) | USP30CDK9 | |
| SCHEMBL17632154 | 0.80 | RAB9A (0.38) | CDK9CHRNB2CHRNA4KDM2BCHEK1 | |
| SCHEMBL17632245 | 0.80 | RAB9A (0.38) | CDK9CHRNB2CHRNA4KDM2BCHEK1 | |
| SCHEMBL17632036 | 0.80 | USP30 (0.50) | USP30CHEK1KCNH2 | |
| SCHEMBL17631943 | 0.79 | USP30 (0.49) | USP30CDK9CHEK1HPGDS | |
| SCHEMBL17632326 | 0.79 | USP30 (0.49) | USP30CDK9CHEK1HPGDS | |
| SCHEMBL17632437 | 0.78 | USP30 (0.48) | USP30CHRNB2CHRNA4 | |
| SCHEMBL17632081 | 0.77 | KCNH2 (0.38) | USP30CDK9CHEK1KCNH2SLC6A3 | |
| SCHEMBL17632195 | 0.77 | CPB1 (0.49) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |