Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 9/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764034 | 0.81 | SLC9A1 (0.46) | SLC6A3ADRA1DHTR2CSLC9A1CYP2C9 | |
| SCHEMBL1763854 | 0.76 | RBP4 (0.55) | SLC6A3ADRA1DHTR2CSLC9A1CYP2C9 | |
| SCHEMBL1763177 | 0.72 | SLC9A1 (0.61) | SLC6A3ADRA1DSLC9A1CYP2C9CYP2C19 | |
| SCHEMBL31701697 | 0.72 | SLC9A1 (0.54) | SLC6A3ADRA1DHTR2CSLC9A1CYP2C9 | |
| SCHEMBL1764032 | 0.71 | HTR1A (0.38) | SLC6A3HTR2CHTR1ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8506226 | 0.70 | SLC9A1 (0.48) | SLC6A3ADRA1DSLC9A1CYP2C9CYP2C19 | |
| SCHEMBL1763870 | 0.70 | CHRNB2 (0.51) | SLC6A3ADRA1DHTR2CSLC9A1CYP2C9 | |
| SCHEMBL25894474 | 0.69 | CA12 (0.44) | — | |
| SCHEMBL1763934 | 0.69 | SLC9A1 (0.54) | SLC9A1CYP2C9CYP2C19CYP3A4KCNH2 | |
| SCHEMBL1763871 | 0.69 | ITGB3 (0.38) | SLC6A3SLC9A1HTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118262-A1 | Pyrrolidinyl and Piperidinyl Compounds Useful as NHE-1 Inhibitiors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118262-A1 | Pyrrolidinyl and Piperidinyl Compounds Useful as NHE-1 Inhibitiors | NHERF1, SLC9A1, SLC9A5 | SLC6A3 98/4885ADRA1D 1467/4885HTR2C 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.