Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | ELANE | P08246 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.81 |
| ▸ | HPGD | P15428 | 1/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.81 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.81 |
| ▸ | PPARG | P37231 | 2/20 | 0.75 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Demethylnobiletin SCHEMBL31237479 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| 5-Demethylnobiletin SCHEMBL29606981 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL17963714 | 0.95 | ALDH1A1 (0.91) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL25263457 | 0.93 | ALDH1A1 (0.86) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL1764664 | 0.93 | ALDH1A1 (0.86) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL10997058 | 0.91 | ALDH1A1 (0.88) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL1764085 | 0.91 | ALDH1A1 (0.84) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL25383379 | 0.90 | ALDH1A1 (0.82) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL25225757 | 0.90 | ALDH1A1 (0.82) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| Nobiletin SCHEMBL22092292 | 0.90 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP3A4MAPK1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260115294-A1 | DERIVATIVES OF 5-HYDROXYLATED POLYMETHOXYFLAVONES WITH ENHANCED BIOAVAILABILITY FOR ORAL DELIVERY AND COMPOSITIONS THEREOF | DEEPSENSE BIOTECHNOLOGIES INC (US) | 2026-04-30 | — | — | US | claimed |
| CN-118121649-A | Citrus extract, compound, and use thereof for inhibiting novel coronaviruses | 丰苗生物科技股份有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-118121589-A | Compounds and their use for inhibiting novel coronaviruses | 丰苗生物科技股份有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-118010094-A | Liquid phase analysis method for multiple chemical components in Xinhui dried orange peel | 江门市五邑中医院 | 2024-05-10 | — | — | CN | claimed |
| CN-115902028-A | Method for determining contents of 17 effective components in dried orange peel by using UPLC-MS/MS | 天津中医药大学 | 2023-04-04 | — | — | CN | claimed |
| CN-115119913-A | Beverage with whitening, liver nourishing and eye protecting effects and preparation method thereof | 梁和标 | 2022-09-30 | — | — | CN | claimed |
| CN-114890972-A | Method for preparing demethyl nobiletin by degrading nobiletin through microwave synergistic deep co-dissolving reagent | 华南理工大学 | 2022-08-12 | — | — | CN | claimed |
| CN-113368048-B | Process for preparing high internal phase emulsions having self-stabilizing ability | 华中农业大学 | 2022-07-01 | — | — | CN | claimed |
| CN-114146124-A | Application of phyllanthus emblica embryo polymethoxylated flavonoids compound in preparation of antioxidant | 中山大学 | 2022-03-08 | — | — | CN | claimed |
| CN-114053346-A | Application of phyllanthus emblica embryo polymethoxylated flavonoids compound in preparation of blood fat reducing product | 中山大学 | 2022-02-18 | — | — | CN | claimed |
| WO-2007024982-A2 | METHODS FOR MANAGING ADIPOCYTE FAT ACCUMULATION | WELLGEN, INC. (US) | 2007-03-01 | — | — | WO | claimed |
| WO-2006132879-A2 | SOFT GEL CAPSULES CONTAINING POLYMETHOXYLATED FLAVONES AND PALM OIL TOCOTRIENOLS | SOFT GEL TECHNOLOGIES, INC. (US) | 2006-12-14 | — | — | WO | claimed |
| US-20060003947-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | THE CIT GROUP/CREDIT FINANCE, INC. | 2006-01-05 | — | — | US | claimed |
| US-20050249803-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | SOFT GEL TECHNOLOGIES, INC. | 2005-11-10 | — | — | US | claimed |
| EP-1278417-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK Synergie (CA) | 2003-01-29 | — | — | EP | claimed |
| WO-2001070029-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK SYNERGIE (CA) | 2001-09-27 | — | — | WO | claimed |
| US-6184246-B1 | Inhibition of cytokine production by polymethoxylated flavones | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2001-02-06 | — | — | US | claimed |
| EP-0605261-B1 | Use of a flavone derivative as taste modifier and a method of modifying taste | SAN EI GEN FFI INC (JP) | 1999-09-15 | — | — | EP | claimed |
| US-5580545-A | ADDING FLAVONE DERIVATIVES TO FOODS, BEVERAGES OR TOILETRIES TO ENHANCE OR REDUCE FLAVORS | SAN-EI GEN F.F.I., INC. (JP) | 1996-12-03 | — | — | US | claimed |
| EP-0605261-A2 | A taste modifier and a method of modifying taste | SAN-EI GEN F.F.I., INC. (JP) | 1994-07-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050249803-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | TTPA, CCNE2, PTGES | ALDH1A1 2980/4885MAPT 1749/4885CYP3A4 1187/4885 |
| US-20060003947-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | TTPA, PLA2G10, GSTO1 | ALDH1A1 1764/4885MAPT 3282/4885CYP3A4 890/4885 |
| US-20260115294-A1 | DERIVATIVES OF 5-HYDROXYLATED POLYMETHOXYFLAVONES WITH ENHANCED BIOAVAILABILITY FOR ORAL DELIVERY AND COMPOSITIONS THEREOF | PLIN3, PNLIP, FABP2 | ALDH1A1 2873/4885MAPT 4716/4885CYP3A4 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.