Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17661791 | 0.86 | NPSR1 (0.43) | PKMMEN1KMT2AMMP2MMP1 | |
| SCHEMBL16213232 | 0.82 | NPSR1 (0.48) | PKMKMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL16212863 | 0.80 | MMP1 (0.50) | RAB9APKMKMT2ALMNAUSP2 | |
| SCHEMBL17661790 | 0.80 | KMT2A (0.45) | MEN1KMT2ALMNAALDH1A1MMP2 | |
| SCHEMBL17651690 | 0.77 | FKBP1A (0.43) | PKMKMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18221853 | 0.77 | KMT2A (0.47) | PKMMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL18221868 | 0.72 | MMP2 (0.47) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL22633433 | 0.72 | NCOA1 (0.72) | RAB9ANCOA1NCOA3PKMMEN1 | |
| SCHEMBL20362575 | 0.71 | ATM (0.40) | MEN1KMT2ATAAR1USP2ALDH1A1 | |
| SCHEMBL18221887 | 0.70 | NPSR1 (0.58) | RAB9AKMT2ALMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017441-B2 | Direct anti-markovnikov addition of acids to alkenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2018-07-10 | — | — | US | disclosed |
| US-20160096791-A1 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | UNIV NORTH CAROLINA (US) | 2016-04-07 | — | — | US | disclosed |
| US-20160096791-A1 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | UNIV NORTH CAROLINA (US) | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096791-A1 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | HAO2, DUOX2, PDK2 | RAB9A 3720/4885NCOA1 2688/4885NCOA3 2964/4885 |
| US-10017441-B2 | Direct anti-markovnikov addition of acids to alkenes | HAO2, DUOX2, PDK2 | RAB9A 3720/4885NCOA1 2688/4885NCOA3 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.