Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17661790 | 0.94 | KMT2A (0.45) | NPSR1MMP2ELANEKMT2AL3MBTL1 | |
| SCHEMBL17651690 | 0.88 | FKBP1A (0.43) | MMP2KMT2AFKBP1APKMMAPT | |
| SCHEMBL16212863 | 0.86 | MMP1 (0.50) | NPSR1MMP2KMT2AFKBP1AGAA | |
| SCHEMBL17661791 | 0.85 | NPSR1 (0.43) | NPSR1MMP2KMT2APKML3MBTL1 | |
| SCHEMBL18221853 | 0.83 | KMT2A (0.47) | NPSR1MMP2ELANEKMT2APKM | |
| SCHEMBL17651682 | 0.82 | RAB9A (0.50) | NPSR1MMP2KMT2APKMMAPT | |
| SCHEMBL3832921 | 0.81 | NPSR1 (0.55) | NPSR1ELANEFKBP1AGAAPKM | |
| SCHEMBL3832918 | 0.81 | NPSR1 (0.55) | NPSR1ELANEFKBP1AGAAPKM | |
| SCHEMBL18221887 | 0.78 | NPSR1 (0.58) | NPSR1MMP2KMT2AGAAMAPT | |
| SCHEMBL8192516 | 0.74 | GAA (0.55) | NPSR1ELANEKMT2AGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017441-B2 | Direct anti-markovnikov addition of acids to alkenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2018-07-10 | — | — | US | disclosed |
| US-10017441-B2 | Direct anti-markovnikov addition of acids to alkenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2018-07-10 | — | — | US | disclosed |
| EP-3093287-A1 | AN IODINE CATALYSED PROCESS FOR PREPARING HETEROCYCLIC NITROGEN-CONTAINING COMPOUNDS | Fundació Institut Català D'investigació Quimica (ES) | 2016-11-16 | — | — | EP | disclosed |
| EP-3093287-A1 | AN IODINE CATALYSED PROCESS FOR PREPARING HETEROCYCLIC NITROGEN-CONTAINING COMPOUNDS | Fundació Institut Català D'investigació Quimica (ES) | 2016-11-16 | — | — | EP | disclosed |
| US-20160096791-A1 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | UNIV NORTH CAROLINA (US) | 2016-04-07 | — | — | US | disclosed |
| US-20160096791-A1 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | UNIV NORTH CAROLINA (US) | 2016-04-07 | — | — | US | disclosed |
| US-20160096791-A1 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | UNIV NORTH CAROLINA (US) | 2016-04-07 | — | — | US | disclosed |
| WO-2014179648-A2 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096791-A1 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | HAO2, DUOX2, PDK2 | NPSR1 4650/4885MMP2 3738/4885ELANE 2927/4885 |
| US-10017441-B2 | Direct anti-markovnikov addition of acids to alkenes | HAO2, DUOX2, PDK2 | NPSR1 4650/4885MMP2 3738/4885ELANE 2927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.