S-Methylglutathione

S-Methylglutathione

SCHEMBL1767370

CSC[C@H](NC(=O)CC[C@H](N)C(=O)O)C(=O)NCC(=O)O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.71
GSTK1 Q9Y2Q3 1/20 0.71
GLO1 Q04760 3/20 0.66
NOD1 Q9Y239 5/20 0.47
FNTA P49354 2/20 0.43
FNTB P49356 2/20 0.43
PGGT1B P53609 1/20 0.43
FOLH1 Q04609 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
S-Methylglutathione SCHEMBL13157330 1.00 PTGS1 (0.71) PTGS1GSTK1GLO1NOD1FNTA
S-Methylglutathione SCHEMBL13948109 1.00 PTGS1 (0.71) PTGS1GSTK1GLO1NOD1FNTA
S-Methylglutathione SCHEMBL1767369 1.00 PTGS1 (0.71) PTGS1GSTK1GLO1NOD1FNTA
S-Methylglutathione SCHEMBL17997395 0.94 PTGS1 (0.83) PTGS1GSTK1GLO1NOD1FNTA
SCHEMBL12773716 0.91 PTGS1 (0.67) PTGS1GSTK1GLO1NOD1FNTA
SCHEMBL12829399 0.91 PTGS1 (0.67) PTGS1GSTK1GLO1NOD1FNTA
SCHEMBL14066343 0.91 PTGS1 (0.59) PTGS1GSTK1GLO1NOD1FNTA
SCHEMBL858838 0.91 PTGS1 (0.59) PTGS1GSTK1GLO1NOD1FNTA
Oxiglutatione SCHEMBL4362052 0.90 PTGS1 (0.73) PTGS1GSTK1GLO1NOD1FOLH1
Oxiglutatione SCHEMBL19579378 0.90 PTGS1 (0.73) PTGS1GSTK1GLO1NOD1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12050228-B2 Automated sample quality assessment METABOLON, INC. (US) 2024-07-30 US claimed
US-20240240229-A1 METHODS OF ADMINISTERING MONOMETHYL FUMARATE AND PRODRUGS THEREOF HAVING REDUCED SIDE EFFECTS HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT 2024-07-18 US claimed
EP-3270889-B1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES MIRECA MEDICINES GMBH (DE) 2024-02-07 EP claimed
CN-113552261-B Marker for identifying ganoderma curvatus and product thereof and application thereof 中国热带农业科学院环境与植物保护研究所 2023-05-02 CN claimed
US-20220273791-A1 SELECTIVE LOCAL INHIBITION OF TNFR1-MEDIATED FUNCTIONS AT THE SITE OF ANTIGEN/ALLERGEN PRESENTATION BREDEHORST REINHARD (DE) 2022-09-01 US claimed
WO-2022074181-A1 NANOCARRIER FORMULATIONS FOR INHALATION EnhanX Biopharm Inc. (TW) 2022-04-14 WO claimed
EP-3395372-B1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM ENHANX BIOPHARM INC (TW) 2022-04-06 EP claimed
US-20210088539-A1 AUTOMATED SAMPLE QUALITY ASSESSMENT METABOLON, INC. 2021-03-25 US claimed
US-10890592-B2 Automated sample quality assessment METABOLON, INC. (US) 2021-01-12 US claimed
US-20190282692-A1 SELECTIVE LOCAL INHIBITION OF TNFR1-MEDIATED FUNCTIONS AT THE SITE OF ANTIGEN/ALLERGEN PRESENTATION BREDEHORST REINHARD (DE) 2019-09-19 US claimed
CN-102316902-A Glutathione-based drug delivery system TO BBB HOLDING B V 2012-01-11 CN claimed
EP-2398500-A2 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM TO-BBB Holding B.V. (NL) 2011-12-28 EP claimed
US-20110305751-A1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM TO-BBB HOLDING B.V. (NL) 2011-12-15 US claimed
WO-2010095940-A2 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM TO-BBB HOLDING B.V. (NL) 2010-08-26 WO claimed
EP-1853292-B1 PHARMACEUTICAL COMPOSITION COMPRISING GLUTATHIONE COMPOUNDS AND BETALAIN FOR THE PREVENTION AND TREATMENT OF CANCER GERNOT TREUSCH (ES) 2008-12-10 EP claimed
EP-1853292-A1 PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF CANCER Gernot, Treusch (ES) 2007-11-14 EP claimed
US-7226766-B2 S-methylcysteine, S-ethylcysteine, and related S-alkylthiols as antagonists to the effects of S-nitrosothiols and nitric oxide UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2007-06-05 US claimed
WO-2006084768-A1 PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF CANCER GERNOT TREUSCH (ES) 2006-08-17 WO claimed
WO-2002100811-A1 S-METHYLCYSTEINE S-ETHYLCYSTEINE AND RELATED S-ALKYLTHIOLS AS ANTAGONISTS TO THE EFFECTS OF S-NITROSOTHIOLS AND NITRIC OXIDE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2002-12-19 WO claimed
US-20020187137-A1 S-methylcysteine, S-ethylcysteine, and related S-alkylthiols as antagonists to the effects of S-nitrosothiols and nitric oxide UNIVERSITY OF IOWA RESEARCH FOUNDATION 2002-12-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110305751-A1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM GSS, GSTO1, SLC7A11 PTGS1 292/4885GSTK1 13/4885GLO1 93/4885
US-20240240229-A1 METHODS OF ADMINISTERING MONOMETHYL FUMARATE AND PRODRUGS THEREOF HAVING REDUCED SIDE EFFECTS GSTM1, GSTM2, GSTA1 PTGS1 412/4885GSTK1 7/4885GLO1 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.