Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | RARA | P10276 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HNF4A | P41235 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8293242 | 0.81 | RARA (0.48) | RARBRARARARGHNF4AKDM4E | |
| SCHEMBL8699677 | 0.79 | RARA (0.44) | RARBRARAGABRA1GABRB2RARG | |
| SCHEMBL17675521 | 0.79 | RARA (0.53) | RARBRARAGABRA1GABRB2RARG | |
| SCHEMBL6178912 | 0.77 | ALDH1A1 (0.53) | RARBRARARARGMEN1MAPT | |
| SCHEMBL12715256 | 0.77 | RARA (0.43) | RARBRARARARGHSD17B10HPGD | |
| SCHEMBL10694294 | 0.74 | RARB (0.58) | RARBRARARARGHDAC1HDAC6 | |
| SCHEMBL1451551 | 0.74 | NOTUM (0.43) | RARBRARAGABRA1GABRB2SIGMAR1 | |
| SCHEMBL30519847 | 0.74 | NOTUM (0.43) | RARBRARAGABRA1GABRB2SIGMAR1 | |
| SCHEMBL8293243 | 0.73 | RARA (0.48) | RARBRARARARGHNF4AMEN1 | |
| SCHEMBL17675380 | 0.72 | RARA (0.40) | RARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204357-B1 | FLUORESCENT SYNTHETIC RETINOIDS | HIGH FORCE RES LIMITED (GB) | 2022-01-19 | — | — | EP | disclosed |
| CN-107250112-B | Fluorescent synthetic retinoids | 高力研究有限公司 | 2021-04-23 | — | — | CN | disclosed |
| US-10759762-B2 | Fluorescent synthetic retinoids | HIGH FORCE RESEARCH LIMITED (GB) | 2020-09-01 | — | — | US | disclosed |
| US-10759762-B2 | Fluorescent synthetic retinoids | HIGH FORCE RESEARCH LIMITED (GB) | 2020-09-01 | — | — | US | disclosed |
| EP-3204357-A2 | FLUORESCENT SYNTHETIC RETINOIDS | High Force Research Limited (GB) | 2017-08-16 | — | — | EP | disclosed |
| US-20170217893-A1 | Fluorescent Synthetic Retinoids | HIGH FORCE RESEARCH LIMITED (GB) | 2017-08-03 | — | — | US | disclosed |
| US-20170217893-A1 | Fluorescent Synthetic Retinoids | HIGH FORCE RESEARCH LIMITED (GB) | 2017-08-03 | — | — | US | disclosed |
| US-20170217893-A1 | Fluorescent Synthetic Retinoids | HIGH FORCE RESEARCH LIMITED (GB) | 2017-08-03 | — | — | US | disclosed |
| WO-2016055800-A2 | FLUORESCENT SYNTHETIC RETINOIDS | HIGH FORCE RESEARCH LIMITED (GB) | 2016-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759762-B2 | Fluorescent synthetic retinoids | RARB, RXRB, RXRA | RARB 1/4885RARA 4/4885GABRA1 861/4885 |
| US-20170217893-A1 | Fluorescent Synthetic Retinoids | RARB, RXRB, RXRA | RARB 1/4885RARA 4/4885GABRA1 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.