Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 3/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9143502 | 0.86 | GABRA1 (0.38) | RARARARBGABRA1GABRB2BRD4 | |
| SCHEMBL17771804 | 0.82 | SIGMAR1 (0.38) | GABRA1GABRB2MAPTLMNABRD4 | |
| SCHEMBL8293242 | 0.81 | RARA (0.48) | RARARARBMAPTLMNAKMT2A | |
| SCHEMBL17675356 | 0.79 | RARB (0.44) | RARARARBGABRA1GABRB2MAPT | |
| SCHEMBL5736680 | 0.78 | GABRA1 (0.38) | RARARARBGABRA1GABRB2MAPT | |
| SCHEMBL5735661 | 0.78 | GABRA1 (0.38) | RARARARBGABRA1GABRB2MAPT | |
| SCHEMBL12715256 | 0.77 | RARA (0.43) | RARARARBLMNASMN1; SMN2HPGD | |
| SCHEMBL7937173 | 0.77 | GABRA1 (0.42) | GABRA1GABRB2MAPTLMNABRD4 | |
| SCHEMBL6178912 | 0.77 | ALDH1A1 (0.53) | RARARARBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL21750798 | 0.76 | GABRA1 (0.42) | RARARARBGABRA1GABRB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998007716-A2 | HETEROAROTINOIDS-ANTICANCER AGENTS WITH RECEPTOR SPECIFICITY AND TGASE ACTIVITY | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 1998-02-26 | — | — | WO | disclosed |