Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505697 | 0.92 | RECQL (0.44) | RECQLTP53MDM2POLBOPRM1 | |
| SCHEMBL10153079 | 0.80 | RECQL (0.35) | RECQLTP53MDM2POLBCHRM2 | |
| SCHEMBL23049672 | 0.78 | DRD2 (0.44) | DRD2MAOAMAOBBCHECHRM2 | |
| SCHEMBL25800782 | 0.78 | DRD2 (0.41) | DRD2MAOAMAOBBCHECHRM2 | |
| SCHEMBL505689 | 0.78 | SIGMAR1 (0.39) | RECQLTP53MDM2POLBALDH1A1 | |
| SCHEMBL24409946 | 0.71 | ATM (0.35) | DRD2TP53MDM2CHRM2CHRM4 | |
| SCHEMBL21180934 | 0.70 | CHRM2 (0.36) | DRD2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL25800778 | 0.70 | TSHR (0.33) | — | |
| SCHEMBL3609864 | 0.69 | CHRNB2 (0.50) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4619311 | 0.68 | RECQL (0.36) | RECQLPOLBCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556123-B2 | Synthesis of triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2017-01-31 | — | — | US | disclosed |
| US-20160102060-A1 | Synthesis of Triethylenetetramines | PROTEMIX CORPORATION LIMITED (NZ) | 2016-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160102060-A1 | Synthesis of Triethylenetetramines | PNMT, TES, TPR | RECQL 1538/4885DRD2 515/4885MAOA 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.