Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505691 | 0.88 | POLB (0.47) | SIGMAR1KDM1APOLBTACR1KMT2A | |
| SCHEMBL505697 | 0.85 | RECQL (0.44) | POLBKMT2AHTTMEN1TSHR | |
| SCHEMBL17679252 | 0.78 | RECQL (0.38) | POLBALDH1A1RECQLTP53MDM2 | |
| SCHEMBL10153079 | 0.74 | RECQL (0.35) | POLBRECQLTP53MDM2 | |
| SCHEMBL4461053 | 0.69 | TACR1 (0.50) | SIGMAR1TACR1KMT2AMEN1RIPK1 | |
| SCHEMBL21180934 | 0.68 | CHRM2 (0.36) | ALDH1A1P2RX7 | |
| SCHEMBL7493746 | 0.68 | KDM4E (0.55) | SIGMAR1TACR1KMT2AMEN1RIPK1 | |
| SCHEMBL3609864 | 0.67 | CHRNB2 (0.50) | KMT2AMEN1RIPK1ALDH1A1 | |
| SCHEMBL24409946 | 0.66 | ATM (0.35) | TACR1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL1109657 | 0.66 | SIGMAR1 (0.41) | SIGMAR1TACR1TSHRRIPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029203-A1 | Synthesis Of Triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2012-02-02 | — | — | US | claimed |
| EP-1778618-A4 | SYNTHESIS OF TRIETHYLENETETRAMINES | PROTEMIX CORP LTD (NZ) | 2008-07-16 | — | — | EP | claimed |
| EP-1778618-A2 | SYNTHESIS OF TRIETHYLENETETRAMINES | Protemix Corporation Limited (NZ) | 2007-05-02 | — | — | EP | claimed |
| WO-2006027705-A2 | SYNTHESIS OF TRIETHYLENETETRAMINES | PROTEMIX CORPORATION LIMITED (NZ) | 2006-03-16 | — | — | WO | claimed |
| US-20060041170-A1 | starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride | PHILERA NEW ZEALAND LIMITED (NZ) | 2006-02-23 | — | — | US | claimed |
| US-11795150-B2 | Synthesis of triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2023-10-24 | — | — | US | disclosed |
| US-11795150-B2 | Synthesis of triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2023-10-24 | — | — | US | disclosed |
| US-20200148647-A1 | Synthesis of Triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2020-05-14 | — | — | US | disclosed |
| US-20200148647-A1 | Synthesis of Triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2020-05-14 | — | — | US | disclosed |
| US-20170226064-A1 | Synthesis of Triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2017-08-10 | — | — | US | disclosed |
| US-20170226064-A1 | Synthesis of Triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2017-08-10 | — | — | US | disclosed |
| US-20170226064-A1 | Synthesis of Triethylenetetramines | PHILERA NEW ZEALAND LIMITED (NZ) | 2017-08-10 | — | — | US | disclosed |
| US-20100173994-A1 | Synthesis of triethylenetetramines | PROTEMIX CORPORATION LIMITED (NZ) | 2010-07-08 | — | — | US | disclosed |
| US-7582796-B2 | starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride | PROTEMIX CORPORATION LIMITED (NZ) | 2009-09-01 | — | — | US | disclosed |
| US-7582796-B2 | starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride | PROTEMIX CORPORATION LIMITED (NZ) | 2009-09-01 | — | — | US | disclosed |
| US-7582796-B2 | starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride | PROTEMIX CORPORATION LIMITED (NZ) | 2009-09-01 | — | — | US | disclosed |
| EP-1778618-A4 | SYNTHESIS OF TRIETHYLENETETRAMINES | PROTEMIX CORP LTD (NZ) | 2008-07-16 | — | — | EP | disclosed |
| EP-1778618-A2 | SYNTHESIS OF TRIETHYLENETETRAMINES | Protemix Corporation Limited (NZ) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006027705-A2 | SYNTHESIS OF TRIETHYLENETETRAMINES | PROTEMIX CORPORATION LIMITED (NZ) | 2006-03-16 | — | — | WO | disclosed |
| US-20060041170-A1 | starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride | PHILERA NEW ZEALAND LIMITED (NZ) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795150-B2 | Synthesis of triethylenetetramines | PNMT, TES, TPR | SIGMAR1 1752/4885KDM1A 1813/4885POLB 1118/4885 |
| US-20170226064-A1 | Synthesis of Triethylenetetramines | PNMT, TES, TPR | SIGMAR1 1752/4885KDM1A 1813/4885POLB 1118/4885 |
| US-20120029203-A1 | Synthesis Of Triethylenetetramines | PNMT, TES, TPR | SIGMAR1 1752/4885KDM1A 1813/4885POLB 1118/4885 |
| US-20200148647-A1 | Synthesis of Triethylenetetramines | PNMT, TES, TPR | SIGMAR1 1752/4885KDM1A 1813/4885POLB 1118/4885 |
| US-20060041170-A1 | starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride | TET1, TET2, TET3 | SIGMAR1 3134/4885KDM1A 203/4885POLB 334/4885 |
| US-20100173994-A1 | Synthesis of triethylenetetramines | PNMT, TES, TPR | SIGMAR1 1752/4885KDM1A 1813/4885POLB 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.