SCHEMBL176801

SCHEMBL176801

Nc1ccc(S(=O)(=O)O)c(Cl)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
TSHR P16473 4/20 0.62
CYP3A4 P08684 4/20 0.62
RECQL P46063 3/20 0.62
HSD17B10 Q99714 2/20 0.62
THRB P10828 1/20 0.62
HPGD P15428 1/20 0.62
ALOX15 P16050 1/20 0.62
CASP1 P29466 1/20 0.62
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
HSD11B1 P28845 1/20 0.48
RAPGEF4 Q8WZA2 1/20 0.47
NT5E P21589 3/20 0.45
TDP1 Q9NUW8 3/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
CASP6 P55212 3/20 0.45
KDM4E B2RXH2 2/20 0.45
POLB P06746 2/20 0.45
GAA P10253 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31650697 1.00 ALDH1A1 (0.62) ALDH1A1TSHRCYP3A4RECQLHSD17B10
SCHEMBL176866 0.83 ALDH1A1 (0.57) ALDH1A1TSHRCYP3A4RECQLHSD17B10
SCHEMBL1300150 0.83 CYP3A4 (0.55) ALDH1A1TSHRCYP3A4RECQLHSD17B10
SCHEMBL27417258 0.82 ALDH1A1 (0.55) ALDH1A1TSHRCYP3A4RECQLHSD17B10
SCHEMBL1383117 0.81 CA1 (0.55) ALDH1A1TSHRCYP3A4RECQLHSD17B10
SCHEMBL7511717 0.80 RAPGEF4 (0.56) ALDH1A1TSHRCYP3A4RECQLHSD17B10
SCHEMBL31618992 0.79 CYP3A4 (0.52) ALDH1A1TSHRCYP3A4RECQLHSD17B10
SCHEMBL282188 0.79 L3MBTL1 (0.62) ALDH1A1TSHRCYP3A4RECQLHSD17B10
SCHEMBL30431062 0.79 L3MBTL1 (0.62) ALDH1A1TSHRCYP3A4RECQLHSD17B10
SCHEMBL1729184 0.78 HSD11B1 (0.45) TSHRHSD17B10HPGDCASP1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250107976-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2025-04-03 US claimed
WO-2025072691-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR HART TAYLOR (US) 2025-04-03 WO claimed
US-20230301892-A1 COMPOSITIONS AND METHODS FOR ELONGATING CURLY HAIR L'OREAL (FR) 2023-09-28 US claimed
WO-2023154471-A2 COMPOSITIONS AND METHODS FOR STYLING HAIR LAGA STEPHANIE (US) 2023-08-17 WO claimed
US-20230248629-A1 COMPOSITIONS AND METHODS FOR STYLING HAIR L'OREAL (FR) 2023-08-10 US claimed
US-20220202676-A1 COMPOSITIONS FOR ALTERING THE COLOR OF HAIR L'OREAL (FR) 2022-06-30 US claimed
EP-3731801-B1 COMPOSITIONS FOR ALTERING THE COLOR OF HAIR OREAL (FR) 2022-03-09 EP claimed
EP-3731801-A1 COMPOSITIONS FOR ALTERING THE COLOR OF HAIR L'OREAL (FR) 2020-11-04 EP claimed
US-20190201309-A1 COMPOSITIONS FOR ALTERING THE COLOR OF HAIR L'OREAL (FR) 2019-07-04 US claimed
US-9556342-B2 Zwitterionic lignin derivatives EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2017-01-31 US claimed
US-20150135989-A1 ZWITTERIONIC LIGNIN DERIVATIVES CRESTLINE DIRECT FINANCE, L.P. 2015-05-21 US claimed
EP-2120555-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN Heller, Adam (US) 2009-11-25 EP claimed
WO-2008094664-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN HELLER ADAM (US) 2008-08-07 WO claimed
EP-4719612-A1 RINSE-OFF HAIR COSMETIC COMPOSITIONS, METHOD OF TREATING HAIR, METHOD FOR PROVIDING IMPROVED CURLS DEFINITION TO THE HAIR AND USE OF A COMPOSITION L'OREAL (FR) 2026-04-08 EP disclosed
EP-4704790-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS Beautyge, S.L. (ES) 2026-03-11 EP disclosed
WO-2026039882-A1 METHODS FOR REDUCING COLOR FADING IN COLOR-TREATED HAIR L'OREAL (FR) 2026-02-26 WO disclosed
US-4055557-A MONOAZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-25 US disclosed
US-4052444-A DIAZO COUPLERS FOR MONOAZO DYES HOECHST AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed
US-3966705-A Disulfo naphthalene containing fiber-reactive tetrazo dyes CIBA-GEIGY CORPORATION (US) 1976-06-29 US disclosed
US-3933829-A 4-Aminoquinoline derivatives JOHN WYETH & BROTHER LIMITED (EN) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230248629-A1 COMPOSITIONS AND METHODS FOR STYLING HAIR DPM1, NACA, FUT6 ALDH1A1 4127/4885TSHR 4465/4885CYP3A4 4513/4885
US-20190201309-A1 COMPOSITIONS FOR ALTERING THE COLOR OF HAIR TYR, SHH, AADAT ALDH1A1 404/4885TSHR 3883/4885CYP3A4 4284/4885
US-20230301892-A1 COMPOSITIONS AND METHODS FOR ELONGATING CURLY HAIR GLUL, NACA, SHH ALDH1A1 2859/4885TSHR 4654/4885CYP3A4 4740/4885
US-20220202676-A1 COMPOSITIONS FOR ALTERING THE COLOR OF HAIR TYR, SHH, AADAT ALDH1A1 404/4885TSHR 3883/4885CYP3A4 4284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.