Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.71 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.51 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.50 |
| ▸ | HRH2 | P25021 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769379 | 1.00 | CYP3A4 (0.71) | CYP3A4SLC7A5CPB2ALDH1A1TSHR | |
| SCHEMBL17846590 | 0.90 | CYP3A4 (0.67) | CYP3A4SLC7A5CPB2HRH4HRH3 | |
| SCHEMBL17846592 | 0.89 | CYP3A4 (0.65) | CYP3A4SLC7A5CPB2HRH4HRH3 | |
| SCHEMBL17846591 | 0.88 | CYP3A4 (0.63) | CYP3A4SLC7A5HRH4HRH3HRH2 | |
| SCHEMBL21645050 | 0.88 | CYP3A4 (0.63) | CYP3A4SLC7A5HRH4HRH3HRH2 | |
| SCHEMBL18878708 | 0.87 | CYP3A4 (0.57) | CYP3A4SLC7A5ALDH1A1TSHRGABRA1 | |
| Histidine SCHEMBL19974306 | 0.83 | CYP3A4 (1.00) | CYP3A4SLC7A5CPB2ALDH1A1TSHR | |
| Histidine SCHEMBL30852263 | 0.83 | CYP3A4 (1.00) | CYP3A4SLC7A5CPB2ALDH1A1TSHR | |
| D-Histidine SCHEMBL288043 | 0.83 | CYP3A4 (1.00) | CYP3A4SLC7A5CPB2ALDH1A1TSHR | |
| Histidine SCHEMBL388560 | 0.83 | CYP3A4 (1.00) | CYP3A4SLC7A5CPB2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2023-09-12 | — | — | US | disclosed |
| US-11629171-B2 | Beta-hairpin peptidomimetics | SPEXIS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| US-11591365-B2 | BCL9 peptides and variants thereof | WNTRX PHARMACEUTICALS INC. (US) | 2023-02-28 | — | — | US | disclosed |
| CN-115093463-A | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2022-09-23 | — | — | CN | disclosed |
| EP-3201219-B1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-11-17 | — | — | EP | disclosed |
| EP-3201218-B1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-11-03 | — | — | EP | disclosed |
| CN-105324390-B | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2021-10-19 | — | — | CN | disclosed |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | SPEXIS AG (CH) | 2021-09-16 | — | — | US | disclosed |
| CN-105849119-B | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2021-01-19 | — | — | CN | disclosed |
| EP-3280723-B1 | BACKBONE-CYCLIZED PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2021-01-06 | — | — | EP | disclosed |
| US-20160052971-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2016-02-25 | — | — | US | disclosed |
| US-20150307556-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2015-10-29 | — | — | US | disclosed |
| US-9109009-B2 | Template-fixed peptidomimetics with CXCR7 modulating activity | POLYPHOR AG (CH) | 2015-08-18 | — | — | US | disclosed |
| US-20140287986-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | POLYPHOR AG (CH) | 2014-09-25 | — | — | US | disclosed |
| US-8754038-B2 | Template-fixed peptidomimetics with CCR10 antagonistic activity | POLYPHOR AG (CH) | 2014-06-17 | — | — | US | disclosed |
| US-20130225506-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2013-08-29 | — | — | US | disclosed |
| CN-102844327-A | Template-fixed peptidomimetics with CXCR7 modulatory activity | POLYPHOR AG | 2012-12-26 | — | — | CN | disclosed |
| US-20120283168-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | POLYPHOR AG (CH) | 2012-11-08 | — | — | US | disclosed |
| CN-102712676-A | Template-fixed peptidomimetics with CCR10 antagonistic activty | POLYPHOR AG | 2012-10-03 | — | — | CN | disclosed |
| WO-2011060832-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | POLYPHOR AG (CH) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140287986-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | FPR1, FPR3, FPR2 | CYP3A4 3817/4885SLC7A5 3559/4885CPB2 833/4885 |
| US-20120283168-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | CCR10, CCR1, CCRL2 | CYP3A4 4212/4885SLC7A5 1767/4885CPB2 1042/4885 |
| US-20150307556-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | CXCR1, CXCL12, CXCR6 | CYP3A4 4803/4885SLC7A5 760/4885CPB2 2057/4885 |
| US-11629171-B2 | Beta-hairpin peptidomimetics | POLL, POLQ, HBZ | CYP3A4 4821/4885SLC7A5 1303/4885CPB2 977/4885 |
| US-20160052971-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | C1S, POLL, BACE1 | CYP3A4 4534/4885SLC7A5 2721/4885CPB2 319/4885 |
| US-20130225506-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | CXCR1, CXCL12, CXCR6 | CYP3A4 4769/4885SLC7A5 677/4885CPB2 2177/4885 |
| US-20210284693-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, POLQ, POLM | CYP3A4 4842/4885SLC7A5 1534/4885CPB2 569/4885 |
| US-11591365-B2 | BCL9 peptides and variants thereof | BCL9, BCL9L, BCL3 | CYP3A4 4851/4885SLC7A5 4385/4885CPB2 117/4885 |
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLL, BACE1, C1S | CYP3A4 4540/4885SLC7A5 3020/4885CPB2 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.