SCHEMBL17698908

SCHEMBL17698908

CCCCCCCCC[N+](C)(C)Cc1ccccc1.CS(=O)(=O)[O-]

nearest known ligand 0.79

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 known ✓ P07550 1/20 0.47
HTR1A known ✓ P08908 1/20 0.47
ADRA2A known ✓ P08913 1/20 0.47
CHRM1 known ✓ P11229 1/20 0.47
DRD2 known ✓ P14416 1/20 0.47
ADRA2B known ✓ P18089 1/20 0.47
ADRA2C known ✓ P18825 1/20 0.47
SLC6A2 known ✓ P23975 1/20 0.47
HTR2A known ✓ P28223 1/20 0.47
HTR2C known ✓ P28335 1/20 0.47
AGTR1 known ✓ P30556 1/20 0.47
SLC6A4 known ✓ P31645 1/20 0.47
DRD3 known ✓ P35462 1/20 0.47
SLC6A3 known ✓ Q01959 1/20 0.47
GHSR known ✓ Q92847 1/20 0.47
DNM1 Q05193 3/20 0.79
MEN1 O00255 2/20 0.77
KMT2A Q03164 2/20 0.77
MAPK1 P28482 2/20 0.77
SMN1; SMN2 Q16637 2/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL332336 1.00 DNM1 (0.79) DNM1MEN1KMT2AMAPK1SMN1; SMN2
Benzododecinium SCHEMBL331784 1.00 DNM1 (0.79) DNM1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL330866 1.00 DNM1 (0.79) DNM1MEN1KMT2AMAPK1SMN1; SMN2
Cetalkonium SCHEMBL1868434 1.00 DNM1 (0.79) DNM1MEN1KMT2AMAPK1SMN1; SMN2
Sulfuric Acid SCHEMBL2968768 0.95 DNM1 (0.81) DNM1MEN1KMT2AMAPK1SMN1; SMN2
Cetalkonium SCHEMBL14965272 0.95 DNM1 (0.81) DNM1MEN1KMT2AMAPK1SMN1; SMN2
Benzododecinium SCHEMBL11412384 0.95 DNM1 (0.81) DNM1MEN1KMT2AMAPK1SMN1; SMN2
Benzododecinium SCHEMBL330693 0.94 DNM1 (0.79) DNM1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL330483 0.94 DNM1 (0.79) DNM1MEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL330707 0.94 DNM1 (0.79) DNM1MEN1KMT2AMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180087005-A1 Fragrance Compositions Comprising Ionic Liquids THE PROCTER & GAMBLE COMPANY 2018-03-29 US disclosed
US-9840680-B2 Fragrance compositions comprising ionic liquids THE PROCTER & GAMBLE COMPANY (US) 2017-12-12 US disclosed
US-20160115424-A1 FRAGRANCE COMPOSITIONS COMPRISING IONIC LIQUIDS THE PROCTER & GAMBLE COMPANY 2016-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160115424-A1 FRAGRANCE COMPOSITIONS COMPRISING IONIC LIQUIDS CUTA, TRPA1, POLR1C ADRB2 3001/4885HTR1A 738/4885ADRA2A 3408/4885
US-20180087005-A1 Fragrance Compositions Comprising Ionic Liquids CUTA, TRPA1, POLR1C ADRB2 3001/4885HTR1A 738/4885ADRA2A 3408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.