Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.57 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4381619 | 0.98 | CYP3A4 (0.56) | IDO1CYP3A4LMNACYP2C9CYP1A2 | |
| SCHEMBL4264696 | 0.90 | LMNA (0.48) | IDO1CYP3A4LMNACYP2C9CYP1A2 | |
| Hydrochloric Acid SCHEMBL7597445 | 0.85 | LMNA (0.43) | IDO1CYP3A4LMNACYP2C9CYP1A2 | |
| SCHEMBL17705699 | 0.81 | CYP3A4 (0.67) | IDO1CYP3A4LMNACYP2C9CYP1A2 | |
| SCHEMBL17705702 | 0.81 | ALDH1A1 (0.43) | IDO1CYP3A4LMNACYP2C9CYP1A2 | |
| SCHEMBL284700 | 0.80 | CALM1 (0.63) | CYP3A4LMNACYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8094422 | 0.79 | CALM1 (0.92) | IDO1CYP3A4LMNACYP2C9TDP1 | |
| SCHEMBL972712 | 0.79 | CALM1 (0.92) | IDO1CYP3A4LMNACYP2C9TDP1 | |
| SCHEMBL1108578 | 0.78 | TSHR (0.62) | CYP3A4LMNACYP2C9CALM1PLA2G10 | |
| SCHEMBL19187359 | 0.78 | ALDH1A1 (0.65) | CYP3A4LMNACYP2C9CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119194469-B | Method for electrochemically synthesizing amine compound | 山东金科力电源科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119194469-A | Method for electrochemically synthesizing amine compound | 山东金科力电源科技有限公司 | 2024-12-27 | — | — | CN | disclosed |
| EP-2145884-B1 | INDOLEDIONE DERIVATIVE | MSD KK (JP) | 2014-08-06 | — | — | EP | disclosed |
| US-8106086-B2 | Indoledione derivative | MSD K.K. (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20100056597-A1 | INDOLEDIONE DERIVATIVE | MSD K.K. (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2145884-A1 | INDOLEDIONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-01-20 | — | — | EP | disclosed |
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4229463-A | ANTICHOLESTEROL AGENTS FOR REDUCING CHOLESTEROL ESTER CONTENT OF ARTERIAL WALLS | SANDOZ, INC. (US) | 1980-10-21 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056597-A1 | INDOLEDIONE DERIVATIVE | LIPE, IDO1, ADRA1A | IDO1 2/4885CYP3A4 1059/4885LMNA 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.