SCHEMBL1771387

SCHEMBL1771387

Cc1ccc(S(=O)(=O)ONC(=O)OC(C)(C)C)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 9/20 0.43
CA2 P00918 9/20 0.43
CA9 Q16790 7/20 0.43
CA12 O43570 6/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 3/20 0.40
CA14 Q9ULX7 1/20 0.40
TSHR P16473 1/20 0.40
CA4 P22748 1/20 0.40
CA7 P43166 1/20 0.40
PTPN7 P35236 1/20 0.40
F2 P00734 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17973933 0.85 KMT2A (0.39) CA1CA2CA9CA12MEN1
SCHEMBL19966589 0.84 CA12 (0.43) CA1CA2CA9CA12MMP1
SCHEMBL31504508 0.82 ALOX5 (0.51) CA1CA2CA9CA12KMT2A
SCHEMBL973720 0.80 CA1 (0.47) CA1CA2CA9CA12MEN1
SCHEMBL4951056 0.79 ALDH1A1 (0.54) CA1CA2CA9CA12MEN1
SCHEMBL9632713 0.79 MEN1 (0.44) CA1CA2CA9CA12MEN1
SCHEMBL16897446 0.78 PKM (0.50) CA1CA2CA9CA12MEN1
SCHEMBL11794766 0.78 F2 (0.49) CA1CA2CA9CA12MEN1
SCHEMBL497667 0.78 NFKB1 (0.53) CA1CA2MEN1KMT2AMMP1
SCHEMBL31529428 0.77 LMNA (0.42) CA1CA2CA9CA12KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250334596-A1 ISOTOPIC LABELS FOR QUANTITATIVE MASS SPECTROMETRY OF LIPID ISOMERS TEXAS A & M UNIV SYS (US) 2025-10-30 US claimed
CN-119059990-B Preparation method of 1-carbamic acid tert-butyl piperazine 安徽昊帆生物有限公司 2025-02-07 CN claimed
CN-119059990-A Preparation method of 1-carbamic acid tert-butyl piperazine 安徽昊帆生物有限公司 2024-12-03 CN claimed
CN-114478303-A Method for synthesizing carbidopa 浙江野风药业股份有限公司 2022-05-13 CN claimed
US-20260102387-A1 IMMUNOSUPPRESSIVE COMPOUNDS UNIV BASEL (CH) 2026-04-16 US disclosed
US-20250334596-A1 ISOTOPIC LABELS FOR QUANTITATIVE MASS SPECTROMETRY OF LIPID ISOMERS TEXAS A & M UNIV SYS (US) 2025-10-30 US disclosed
US-20250257060-A1 OXADIAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF SUZHOU GENHOUSE BIO CO., LTD. (CN) 2025-08-14 US disclosed
EP-4594304-A2 IMMUNOSUPPRESSIVE COMPOUNDS Universität Basel Vizerektorat Forschung (CH) 2025-08-06 EP disclosed
CN-120044110-A Method for determining lipid chemical structure and ion mobility spectrometry tandem mass spectrometer 株式会社岛津制作所 2025-05-27 CN disclosed
CN-119959392-A Method for identifying unsaturated organic matters and mass spectrum system 株式会社岛津制作所 2025-05-09 CN disclosed
CN-115947690-B Preparation method of indazole molecular building block and application of indazole molecular building block in drug synthesis 安徽医科大学 2025-04-08 CN disclosed
CN-119732939-A Use of Etalocib in preparing medicine for resisting gram positive bacteria infection 华中科技大学协和深圳医院 2025-04-01 CN disclosed
WO-2015026792-A1 ANTIVIRAL COMPOUNDS ALIOS BIOPHARMA, INC. (US) 2015-02-26 WO disclosed
WO-2014071007-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2014-05-08 WO disclosed
WO-2014070964-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2014-05-08 WO disclosed
EP-2227087-B1 CBI DERIVATIVES SUBJECT TO REDUCTIVE ACTIVATION SCRIPPS RESEARCH INST (US) 2013-10-09 EP disclosed
US-8377981-B2 CBI derivatives subject to reductive activation THE SCRIPPS RESEARCH INSTITUTE (US) 2013-02-19 US disclosed
US-20110112163-A1 CBI DERIVATIVES SUBJECT TO REDUCTIVE ACTIVATION SCRIPPS RESEARCH INSTITUTE, THE 2011-05-12 US disclosed
EP-2227087-A1 CBI DERIVATIVES SUBJECT TO REDUCTIVE ACTIVATION The Scripps Research Institute (US) 2010-09-15 EP disclosed
WO-2009064908-A1 CBI DERIVATIVES SUBJECT TO REDUCTIVE ACTIVATION THE SCRIPPS RESEARCH INSTITUTE (US) 2009-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250257060-A1 OXADIAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF HDAC6, HDAC1, HDAC11 CA1 1837/4885CA2 3037/4885CA9 1747/4885
US-20260102387-A1 IMMUNOSUPPRESSIVE COMPOUNDS CHP1, BRD3, IRF3 CA1 3592/4885CA2 3272/4885CA9 4579/4885
US-20110112163-A1 CBI DERIVATIVES SUBJECT TO REDUCTIVE ACTIVATION DBI, CCNI, TDO2 CA1 657/4885CA2 302/4885CA9 621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.