SCHEMBL1774169

SCHEMBL1774169

Brc1ccc(-c2cc3ccccc3s2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.68
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA9 Q16790 1/20 0.58
HSD17B1 P14061 1/20 0.56
HSD17B2 P37059 1/20 0.56
ERN1 O75460 3/20 0.50
ESR1 P03372 4/20 0.47
ESR2 Q92731 4/20 0.47
HDAC2 Q92769 2/20 0.43
PIK3R1 P27986 1/20 0.43
PIK3CA P42336 1/20 0.43
NQO1 P15559 1/20 0.42
NQO2 P16083 1/20 0.42
ALDH1A1 P00352 2/20 0.41
MAPK1 P28482 2/20 0.41
MAOB P27338 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14178356 0.98 APP (0.66) APPCA1CA2CA9HSD17B1
SCHEMBL32677328 0.90 APP (0.81) APPCA1CA2CA9HSD17B1
SCHEMBL27159530 0.90 APP (0.81) APPCA1CA2CA9HSD17B1
SCHEMBL29394950 0.87 APP (0.62) APPCA1CA2CA9HSD17B1
SCHEMBL31589824 0.86 APP (0.56) APPCA1CA2CA9HSD17B1
SCHEMBL20983998 0.85 APP (0.50) APPCA1CA2CA9HSD17B1
SCHEMBL22206277 0.85 HSD17B1 (0.61) APPCA1CA2CA9HSD17B1
SCHEMBL24331944 0.85 APP (0.58) APPCA1CA2CA9HSD17B1
SCHEMBL29939219 0.84 APP (0.54) APPCA1CA2CA9HSD17B1
SCHEMBL30394236 0.84 APP (0.50) APPCA1CA2CA9HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622134-B2 Organic electroluminescent device, and electronic apparatus HODOGAYA CHEMICAL CO., LTD. (JP) 2026-05-05 US disclosed
US-12441684-B2 Organic compound for capping layer and organic light emitting diode comprising the same DONGJIN SEMICHEM CO., LTD. (KR) 2025-10-14 US disclosed
US-12428409-B2 Compound, material for organic electroluminescent elements, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2025-09-30 US disclosed
WO-2025121699-A1 HETEROARYL AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 랩토 2025-06-12 WO disclosed
US-20240352009-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2024-10-24 US disclosed
EP-4424682-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Hodogaya Chemical Co., Ltd. (JP) 2024-09-04 EP disclosed
US-20240179930-A1 ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS HODOGAYA CHEMICAL CO., LTD. (JP) 2024-05-30 US disclosed
CN-117980304-A Amine compound and organic electroluminescent element using same 保土谷化学工业株式会社 2024-05-03 CN disclosed
CN-117715901-A Compound and organic electroluminescent element 保土谷化学工业株式会社 2024-03-15 CN disclosed
EP-4307835-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC EQUIPMENT THEREFOR Hodogaya Chemical Co., Ltd. (JP) 2024-01-17 EP disclosed
CN-103664994-A Benzodithiophene derivative organic electroluminescent material and application thereof KUNSHAN VISIONOX DISPLAY TECH 2014-03-26 CN disclosed
US-7998596-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-08-16 US disclosed
US-7998596-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-08-16 US disclosed
CN-102066337-A 5-hydroxypyrimidine-4-carboxamide compounds DAIICHI SANKYO CO LTD 2011-05-18 CN disclosed
US-20110112103-A1 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-05-12 US disclosed
EP-2177516-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2010-04-21 EP disclosed
US-20090066235-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-03-12 US disclosed
US-20090066235-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-03-12 US disclosed
US-20080106190-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-05-08 US disclosed
US-20080106190-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240352009-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME EZH1, AZI2, EPCAM APP 3192/4885CA1 2301/4885CA2 1454/4885
US-12441684-B2 Organic compound for capping layer and organic light emitting diode comprising the same CAPG, CAPZA1, OCIAD1 APP 3924/4885CA1 3507/4885CA2 3723/4885
US-12622134-B2 Organic electroluminescent device, and electronic apparatus KCNN1, KCNN2, ITGA1 APP 4418/4885CA1 894/4885CA2 722/4885
US-20080106190-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME EML4, SLC18A2, SLC18A3 APP 547/4885CA1 3673/4885CA2 3086/4885
US-12428409-B2 Compound, material for organic electroluminescent elements, organic electroluminescent element, and electronic device L1CAM, MLX, LEF1 APP 1648/4885CA1 2635/4885CA2 2695/4885
US-20110112103-A1 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND EPOR, CBR1, CBR3 APP 3999/4885CA1 3084/4885CA2 3253/4885
US-20090066235-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME DDC, TYR, EML4 APP 770/4885CA1 3806/4885CA2 3077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.