Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.52 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | CTSB | P07858 | 3/20 | 0.52 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16312552 | 0.91 | CTSS (0.48) | CTSSCTSLCTSBCTSKALDH1A1 | |
| SCHEMBL16312555 | 0.91 | CTSS (0.48) | CTSSCTSLCTSBCTSKALDH1A1 | |
| Hydrochloric Acid SCHEMBL17683922 | 0.90 | CTSS (0.47) | CTSSCTSLCTSBCTSKALDH1A1 | |
| SCHEMBL16312551 | 0.86 | CTSS (0.47) | CTSSCTSLCTSBCTSKALDH1A1 | |
| SCHEMBL16312553 | 0.83 | STS (0.46) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1840727 | 0.83 | CTSL (0.48) | CTSSCTSLCTSBCTSKALDH1A1 | |
| SCHEMBL16391269 | 0.81 | FAAH (0.60) | CTSSCTSLCTSBCTSKFAAH | |
| SCHEMBL2707114 | 0.81 | CTSS (0.47) | CTSSCTSLCTSBCTSKALDH1A1 | |
| SCHEMBL7528358 | 0.80 | CTSL (0.56) | CTSSCTSLCTSBCTSKKMT2A | |
| SCHEMBL550418 | 0.80 | CTSL (0.56) | CTSSCTSLCTSBCTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9636346-B2 | Alpha-oxoacyl amino-caprolactam derivative | SEIKAGAKU CORPORATION (JP) | 2017-05-02 | — | — | US | disclosed |
| US-20160375031-A1 | ALPHA-OXOACYL AMINO-CAPROLACTAM DERIVATIVE | SEIKAGAKU KOGYO CO LTD (JP) | 2016-12-29 | — | — | US | disclosed |
| US-9481707-B2 | α-oxoacyl amino-caprolactam derivative | SEIKAGAKU CORPORATION (JP) | 2016-11-01 | — | — | US | disclosed |
| US-20160137691-A1 | ALPHA-OXOACYL AMINO-CAPROLACTAM DERIVATIVE | SEIKAGAKU CORPORATION (JP) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160375031-A1 | ALPHA-OXOACYL AMINO-CAPROLACTAM DERIVATIVE | OGFRL1, ARGLU1, COL1A1 | CTSS 1443/4885CTSL 69/4885CTSB 805/4885 |
| US-20160137691-A1 | ALPHA-OXOACYL AMINO-CAPROLACTAM DERIVATIVE | COL2A1, ARGLU1, COL1A1 | CTSS 1538/4885CTSL 107/4885CTSB 1001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.