Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1773617 | 0.85 | FAAH (0.41) | FAAH | |
| SCHEMBL1970503 | 0.84 | KDM4E (0.39) | FAAH | |
| SCHEMBL1774898 | 0.81 | GAA (0.48) | GPR119FAAHGAATHRBSMN1; SMN2 | |
| SCHEMBL1775285 | 0.80 | GPR119 (0.47) | GPR119FAAHGRM5GAATHRB | |
| SCHEMBL1775405 | 0.80 | GPR119 (0.50) | GPR119FAAHGRM5GBA1 | |
| SCHEMBL1775429 | 0.79 | GPR119 (0.49) | GPR119THRBSTS | |
| SCHEMBL1773435 | 0.78 | GPR119 (0.44) | GPR119FAAHNAMPTACHEHPGDS | |
| SCHEMBL1120331 | 0.78 | GPR119 (0.44) | GPR119FAAHNAMPT | |
| SCHEMBL1774574 | 0.78 | GPR119 (0.52) | GPR119FAAHNAMPTACHEGAA | |
| SCHEMBL1773618 | 0.78 | GPR119 (0.44) | GPR119FAAHNAMPTACHEHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334669-B1 | HETEROCYCLYL-SUBSTITUTED THIAZOLES AS PLANT PROTECTION AGENTS | BAYER IP GMBH (DE) | 2015-12-23 | — | — | EP | disclosed |
| EP-2334669-A1 | HETEROCYCLYL-SUBSTITUTED THIAZOLES AS PLANT PROTECTION AGENTS | Bayer CropScience AG (DE) | 2011-06-22 | — | — | EP | disclosed |
| US-7943774-B2 | Heterocyclyl-substituted thiazoles as crop protection agents | BAYER CROPSCIENCE AG (DE) | 2011-05-17 | — | — | US | disclosed |
| US-20100137245-A1 | Heteerocyclyl-substituted thiazoles as crop protection agents | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | disclosed |
| WO-2010037479-A1 | HETEROCYCLYL-SUBSTITUTED THIAZOLES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137245-A1 | Heteerocyclyl-substituted thiazoles as crop protection agents | CYP8B1, CYP51A1, HPD | GPR119 3388/4885FAAH 4083/4885NAMPT 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.