SCHEMBL1970503

SCHEMBL1970503

CCCCOC(=O)N1CCC(c2nc(C#Cc3cccc4ccccc34)cs2)CC1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
FAAH O00519 12/20 0.38
P2RY12 Q9H244 3/20 0.38
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.36
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1775738 0.84 GPR119 (0.44) FAAH
SCHEMBL1773617 0.82 FAAH (0.41) FAAH
SCHEMBL3376521 0.79 FAAH (0.38) KDM4EPOLBFAAHP2RY12KMT2A
SCHEMBL1773356 0.73 GAA (0.42) KDM4EPOLBLMNA
SCHEMBL13419963 0.69 P2RY12 (0.51) P2RY12
SCHEMBL13419600 0.69 P2RY12 (0.45) KDM4EFAAHP2RY12KMT2AMAPT
SCHEMBL8922008 0.69 CHRM4 (0.59) POLBKMT2AMAPTLMNA
SCHEMBL4831481 0.69 L3MBTL1 (0.46) POLBMAPTLMNA
SCHEMBL1939689 0.69 SMN1; SMN2 (0.42) POLBKMT2AMAPTLMNA
SCHEMBL13419619 0.68 PIM1 (0.53) P2RY12KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2334669-A1 HETEROCYCLYL-SUBSTITUTED THIAZOLES AS PLANT PROTECTION AGENTS Bayer CropScience AG (DE) 2011-06-22 EP disclosed
WO-2010037479-A1 HETEROCYCLYL-SUBSTITUTED THIAZOLES AS PLANT PROTECTION AGENTS BAYER CROPSCIENCE AG (DE) 2010-04-08 WO disclosed