Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | BCL9 | O00512 | 2/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16109144 | 0.83 | FFAR2 (0.46) | PDE4DCTSA | |
| SCHEMBL16108140 | 0.81 | PAX8 (0.47) | PDE4DUSP30 | |
| SCHEMBL16111924 | 0.78 | MKNK1 (0.56) | HPSECYP1A2CYP3A4 | |
| SCHEMBL7603613 | 0.77 | RARA (0.55) | P4HBPTGDR2PDE4DCTSAHPSE | |
| SCHEMBL28788990 | 0.75 | ROCK2 (0.51) | P4HBPTGDR2ROCK2ROCK1HPSE | |
| SCHEMBL16108312 | 0.75 | KAT6A (0.44) | USP30 | |
| SCHEMBL9469524 | 0.73 | HTR7 (0.55) | PDE4DKITCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1812722 | 0.73 | KDM1A (0.49) | PTGDR2BACE1PDE4DCTSAKDM1A | |
| SCHEMBL4974725 | 0.73 | AR (0.52) | PTGDR2BACE1PDE4DCTSAKDM1A | |
| SCHEMBL1811323 | 0.72 | LPAR1 (0.51) | PTGDR2BCL9CTNNB1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353089-B2 | Compositions and methods for the treatment of malaria | SAINT LOUIS UNIVERSITY (US) | 2016-05-31 | — | — | US | disclosed |