SCHEMBL177827

SCHEMBL177827

C=CC(=O)NCCCS(=O)(=O)O.[Na]

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.56
ZDHHC2 Q9UIJ5 1/20 0.56
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
EPHX2 P34913 1/20 0.41
TGM2 P21980 13/20 0.41
MAPT P10636 1/20 0.39
GAA P10253 1/20 0.38
APP P05067 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25112 0.98 ZDHHC20 (0.58) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
Ammonia Solution, Strong SCHEMBL5086228 0.96 ZDHHC20 (0.56) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
Ammonia Solution, Strong SCHEMBL5086225 0.96 ZDHHC20 (0.56) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL2785000 0.96 ZDHHC20 (0.56) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL177994 0.94 ZDHHC20 (0.58) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL462110 0.92 ZDHHC20 (0.61) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL4807878 0.92 ZDHHC20 (0.61) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL11695495 0.92 ZDHHC20 (0.61) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL5050870 0.92 ZDHHC20 (0.61) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL11694993 0.92 ZDHHC20 (0.61) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240061337-A1 LITHOGRAPHIC PRINTING PLATE PRECURSORS, METHODS OF USING AND MANUFACTURE BANK OF AMERICA, N.A., AS AGENT 2024-02-22 US disclosed
WO-2024030272-A1 LITHOGRAPHIC PRINTING PLATE PRECURSORS, METHODS OF USING AND MANUFACTURE EASTMAN KODAK COMPANY (US) 2024-02-08 WO disclosed
EP-4017623-A1 MICROCAPSULES ENCAPSULATING HYDROPHOBIC MATERIALS Koehler Paper SE (DE) 2022-06-29 EP disclosed
WO-2021032864-A1 MICROCAPSULES ENCAPSULATING HYDROPHOBIC MATERIALS PAPIERFABRIK AUGUST KOEHLER SE (DE) 2021-02-25 WO disclosed
EP-3782724-A1 ENCAPSULATION OF REACTIVE MATERIALS Papierfabrik August Koehler SE (DE) 2021-02-24 EP disclosed
EP-2386538-B1 N-(1-HYDROXYETHYL)CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME SHOWA DENKO KK (JP) 2015-07-29 EP disclosed
US-8697912-B2 N-(1-hydroxyethyl) carboxamide compound and process for producing same SHOWA DENKO K.K. (JP) 2014-04-15 US disclosed
US-20110294974-A1 N-(1-HYDROXYETHYL ) CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME SHOWA DENKO K.K. (JP) 2011-12-01 US disclosed
EP-2386538-A1 N-(1-HYDROXYETHYL)CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME Showa Denko K.K. (JP) 2011-11-16 EP disclosed
EP-1115663-B1 METHOD OF DEWATERING DIFFICULT SLUDGES NALCO CHEMICAL CO (US) 2006-09-20 EP disclosed
EP-0473881-B1 Liquid absorption agent SHOWA DENKO KK (JP) 2001-11-07 EP disclosed
EP-1115663-A1 METHOD OF DEWATERING DIFFICULT SLUDGES NALCO CHEMICAL COMPANY (US) 2001-07-18 EP disclosed
US-6083404-A MIXING WITH AN COAGULANT AND FLOCCULANT NALCO CHEMICAL COMPANY (US) 2000-07-04 US disclosed
WO-2000017112-A1 METHOD OF DEWATERING DIFFICULT SLUDGES NALCO CHEMICAL COMPANY (US) 2000-03-30 WO disclosed
US-5788950-A Method for the synthesis of mixed metal oxide powders SHOWA DENKO K.K. (JP) 1998-08-04 US disclosed
US-5744118-A MIXING ABSORBENT RESIN AND METAL SALTS, SWELLING AND GELATION, ADJUSTMENT OF PH, PYROLYSIS AND ROASTING SHOWA DENKO K.K. (JP) 1998-04-28 US disclosed
US-5407996-A Contacting with an aqueous solution of metal ion or metal oxide to form a gel; calcining SHOWA DENKO K.K. (JP) 1995-04-18 US disclosed
US-5300606-A Crosslinked N-vinylamide resin SHOWA DENKO K.K. (JP) 1994-04-05 US disclosed
EP-0473881-A1 Liquid absorption agent SHOWA DENKO KABUSHIKI KAISHA (JP) 1992-03-11 EP disclosed
EP-0123576-A2 Acrylonitrile copolymers, latex compositions and protective overcoats for photographic elements containing acrylonitrile copolymers EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294974-A1 N-(1-HYDROXYETHYL ) CARBOXAMIDE COMPOUND AND PROCESS FOR PRODUCING SAME ADH1A, ADH1C, CNKSR1 ZDHHC20 2180/4885ZDHHC2 1414/4885ALDH1A1 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.