Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.73 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.73 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.73 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.73 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.73 |
| ▸ | DHFR | P00374 | 1/20 | 0.73 |
| ▸ | MPO | P05164 | 1/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.73 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.73 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.73 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7925344 | 0.85 | PTGS2 (0.76) | PTGS2LMNAMEN1KMT2APTGS1 | |
| Mefenamic Acid SCHEMBL29350572 | 0.85 | PTGS2 (1.00) | PTGS2LMNAMEN1KMT2APTGS1 | |
| Mefenamic Acid SCHEMBL29465887 | 0.85 | PTGS2 (1.00) | PTGS2LMNAMEN1KMT2APTGS1 | |
| Mefenamic Acid SCHEMBL6421234 | 0.85 | PTGS2 (1.00) | PTGS2LMNAMEN1KMT2APTGS1 | |
| Mefenamic Acid SCHEMBL3544 | 0.85 | PTGS2 (1.00) | PTGS2LMNAMEN1KMT2APTGS1 | |
| Mefenamic Acid SCHEMBL29355128 | 0.85 | PTGS2 (1.00) | PTGS2LMNAMEN1KMT2APTGS1 | |
| Mefenamic Acid SCHEMBL29282578 | 0.83 | PTGS2 (0.97) | PTGS2LMNAMEN1KMT2APTGS1 | |
| Mefenamic Acid SCHEMBL28663310 | 0.83 | PTGS2 (0.97) | PTGS2LMNAMEN1KMT2APTGS1 | |
| Mefenamic Acid SCHEMBL678182 | 0.83 | PTGS2 (0.97) | PTGS2LMNAMEN1KMT2APTGS1 | |
| Mefenamic Acid SCHEMBL16179956 | 0.83 | PTGS2 (0.97) | PTGS2LMNAMEN1KMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168160-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2016-06-16 | — | — | US | disclosed |
| US-20160151352-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2016-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160151352-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | OPRM1, OPRK1, OPRD1 | PTGS2 119/4885LMNA 3727/4885MEN1 4821/4885 |
| US-20160168160-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | OPRM1, OPRK1, OPRD1 | PTGS2 187/4885LMNA 4458/4885MEN1 4879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.