Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 4/20 | 0.35 |
| ▸ | CPT2 | P23786 | 2/20 | 0.34 |
| ▸ | CPT1A | P50416 | 2/20 | 0.34 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17801089 | 0.90 | ALDH1A1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL17801066 | 0.86 | HCRTR1 (0.40) | USP30HCRTR1HCRTR2RXRARXRB | |
| SCHEMBL17801038 | 0.77 | CMKLR1 (0.35) | CMKLR1RXRARXRBRXRG | |
| SCHEMBL17801065 | 0.76 | ALDH1A1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL5373251 | 0.75 | CMKLR1 (0.38) | CMKLR1RXRARXRBRXRG | |
| SCHEMBL5373390 | 0.73 | CSNK1A1 (0.38) | CMKLR1RXRARXRBRXRG | |
| SCHEMBL5374037 | 0.73 | KDM1A (0.37) | CMKLR1RXRARXRBRXRG | |
| SCHEMBL5378280 | 0.73 | RXRA (0.36) | CMKLR1RXRARXRBRXRG | |
| SCHEMBL5375543 | 0.72 | ATR (0.39) | CMKLR1RXRARXRBRXRG | |
| SCHEMBL4084335 | 0.72 | RXRA (0.42) | CMKLR1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016089977-A1 | SUBSTITUTED INDAZOLE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | CELGENE CORPORATION (US) | 2016-06-09 | — | — | WO | disclosed |