Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 17/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 16/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17801065 | 0.89 | ALDH1A1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL17801026 | 0.86 | USP30 (0.37) | HCRTR1HCRTR2USP30RXRARXRB | |
| SCHEMBL17801089 | 0.76 | ALDH1A1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL17801073 | 0.75 | TLR8 (0.35) | RXRARXRBRXRG | |
| SCHEMBL17801094 | 0.75 | PLK1 (0.35) | RXRARXRBRXRG | |
| SCHEMBL17801039 | 0.74 | HCAR3 (0.43) | RXRARXRBRXRG | |
| SCHEMBL3366778 | 0.73 | HCRTR1 (0.58) | HCRTR1HCRTR2USP30HSD11B1 | |
| SCHEMBL3370370 | 0.72 | HCRTR1 (0.60) | HCRTR1HCRTR2USP30HSD11B1 | |
| SCHEMBL17801031 | 0.72 | CNR2 (0.35) | RXRARXRBRXRG | |
| SCHEMBL3659576 | 0.72 | HCRTR1 (0.50) | HCRTR1HCRTR2USP30HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016089977-A1 | SUBSTITUTED INDAZOLE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | CELGENE CORPORATION (US) | 2016-06-09 | — | — | WO | disclosed |