Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 11/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15240650 | 0.89 | HSD11B1 (0.47) | TLR9TLR8TLR7MGLLUSP30 | |
| SCHEMBL17801068 | 0.86 | HTT (0.47) | TLR9TLR8TLR7 | |
| SCHEMBL17801024 | 0.82 | FASN (0.46) | TLR9TLR8TLR7USP30CPT2 | |
| SCHEMBL17801083 | 0.82 | HPGDS (0.45) | TLR9TLR8TLR7 | |
| SCHEMBL12231361 | 0.78 | USP30 (0.58) | MGLLUSP30HTR2B | |
| SCHEMBL2731621 | 0.78 | HPGDS (0.46) | TLR9TLR8TLR7USP30 | |
| SCHEMBL2731625 | 0.78 | HPGDS (0.46) | TLR9TLR8TLR7USP30 | |
| SCHEMBL12231269 | 0.78 | KIT (0.52) | MGLLUSP30HTR2BKIT | |
| SCHEMBL17801043 | 0.70 | GPR119 (0.48) | TLR9TLR8TLR7 | |
| SCHEMBL12231359 | 0.69 | CPT1A (0.54) | MGLLUSP30HTR2BCPT2CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016089977-A1 | SUBSTITUTED INDAZOLE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | CELGENE CORPORATION (US) | 2016-06-09 | — | — | WO | disclosed |