Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21499221 | 0.84 | ALDH1A1 (0.57) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL17801223 | 0.83 | MAPT (0.51) | KDM4EALDH1A1MAPTGAATSHR | |
| SCHEMBL18470907 | 0.82 | TDP1 (0.52) | USP2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL30874176 | 0.81 | HTT (0.55) | USP2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17801210 | 0.81 | HTT (0.55) | USP2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL23610369 | 0.81 | KDM4E (0.71) | USP2KDM4ECHEK1ALDH1A1MEN1 | |
| SCHEMBL17737082 | 0.81 | KDM4E (0.71) | USP2KDM4ECHEK1ALDH1A1MEN1 | |
| SCHEMBL18470911 | 0.80 | GPR119 (0.43) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27515415 | 0.78 | CA12 (0.64) | USP2KDM4ECHEK1ALDH1A1MAPT | |
| SCHEMBL10486194 | 0.78 | HPGD (0.51) | KDM4EALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238169-A1 | PROCESS FOR PREPARING A COMPOUND OF FORMULA (XIII) | PULMOCIDE LIMITED (GB) | 2021-08-05 | — | — | US | disclosed |
| US-11008307-B2 | Compounds which are used in the preparation of the compound of formula (I) | PULMOCIDE LIMITED (GB) | 2021-05-18 | — | — | US | disclosed |
| US-20200399253-A1 | COMPOUNDS WHICH ARE USED IN THE PREPARATION OF THE COMPOUND OF FORMULA (I) | PULMOCIDE LIMITED (GB) | 2020-12-24 | — | — | US | disclosed |
| US-10800762-B2 | Compounds which are used in the preparation of the compound of formula (II) | PULMOCIDE LIMITED (GB) | 2020-10-13 | — | — | US | disclosed |
| EP-3227277-B1 | ANTIMYCOTIC COMPOUND | PULMOCIDE LTD (GB) | 2020-02-05 | — | — | EP | disclosed |
| US-20200031809-A1 | COMPOUNDS WHICH ARE USED IN THE PREPARATION OF THE COMPOUND OF FORMULA (II) | PULMOCIDE LIMITED (GB) | 2020-01-30 | — | — | US | disclosed |
| US-20190023696-A1 | COMPOUND | PULMOCIDE LIMITED (GB) | 2019-01-24 | — | — | US | disclosed |
| US-10093659-B2 | Compound useful to treat mycoses | PLUMOCIDE LIMITED (GB) | 2018-10-09 | — | — | US | disclosed |
| EP-3227277-A1 | ANTIMYCOTIC COMPOUND | Pulmocide Limited (GB) | 2017-10-11 | — | — | EP | disclosed |
| US-20170037035-A1 | COMPOUND | PULMOCIDE LIMITED (GB) | 2017-02-09 | — | — | US | disclosed |
| WO-2016087878-A1 | ANTIMYCOTIC COMPOUND | PULMOCIDE LIMITED (GB) | 2016-06-09 | — | — | WO | disclosed |
| WO-2016087878-A1 | ANTIMYCOTIC COMPOUND | PULMOCIDE LIMITED (GB) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023696-A1 | COMPOUND | DPM1, MYC, ERG28 | USP2 3678/4885KDM4E 1212/4885CHEK1 4427/4885 |
| US-20200031809-A1 | COMPOUNDS WHICH ARE USED IN THE PREPARATION OF THE COMPOUND OF FORMULA (II) | CYP11B2, SDHB, SDHA | USP2 3468/4885KDM4E 2947/4885CHEK1 3904/4885 |
| US-10093659-B2 | Compound useful to treat mycoses | DPM1, MYC, ERG28 | USP2 4183/4885KDM4E 2481/4885CHEK1 4349/4885 |
| US-20200399253-A1 | COMPOUNDS WHICH ARE USED IN THE PREPARATION OF THE COMPOUND OF FORMULA (I) | CYP11B2, CYP11B1, CYP21A2 | USP2 4265/4885KDM4E 3111/4885CHEK1 4050/4885 |
| US-11008307-B2 | Compounds which are used in the preparation of the compound of formula (I) | CYP11B2, CYP11B1, CYP21A2 | USP2 4265/4885KDM4E 3111/4885CHEK1 4050/4885 |
| US-10800762-B2 | Compounds which are used in the preparation of the compound of formula (II) | CYP11B2, SDHB, SDHA | USP2 3468/4885KDM4E 2947/4885CHEK1 3904/4885 |
| US-20210238169-A1 | PROCESS FOR PREPARING A COMPOUND OF FORMULA (XIII) | CYP2F1, CYP4A11, CYP4F11 | USP2 2108/4885KDM4E 2229/4885CHEK1 4415/4885 |
| US-20170037035-A1 | COMPOUND | DPM1, MYC, ERG28 | USP2 3678/4885KDM4E 1212/4885CHEK1 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.