Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 1/20 | 0.38 | |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17803641 | 1.00 | PDF (0.38) | PDFSSTR3HTTNPC1RAB9A | |
| SCHEMBL19803950 | 0.90 | HTR2A (0.37) | PDFSSTR3DPP8DPP9TGM2 | |
| SCHEMBL16847982 | 0.90 | HTR2A (0.37) | PDFSSTR3DPP8DPP9TGM2 | |
| SCHEMBL17803629 | 0.90 | HTR2A (0.37) | PDFSSTR3DPP8DPP9TGM2 | |
| SCHEMBL17801960 | 0.88 | ITGB1 (0.34) | EHMT2 | |
| SCHEMBL16847844 | 0.88 | OPRM1 (0.33) | — | |
| SCHEMBL17813693 | 0.87 | RAB9A (0.36) | RAB9A | |
| SCHEMBL22698603 | 0.87 | SIRT2 (0.35) | — | |
| SCHEMBL17801794 | 0.87 | SSTR3 (0.32) | PDFSSTR3USP21 | |
| SCHEMBL21695294 | 0.86 | HDAC3 (0.37) | NPC1RAB9ASMN1; SMN2EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3226908-A1 | ANTI-STAPHYLOCOCCUS AUREUS ANTIBODY RIFAMYCIN CONJUGATES AND USES THEREOF | F.HOFFMANN-LA ROCHE AG (CH) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016090040-A1 | ANTI-STAPHYLOCOCCUS AUREUS ANTIBODY RIFAMYCIN CONJUGATES AND USES THEREOF | GENENTECH, INC. (US) | 2016-06-09 | — | — | WO | disclosed |