SCHEMBL1780657

SCHEMBL1780657

CCCn1c(=O)c2[nH]c(-c3cc(OCC(=O)N4CCN(c5ccccc5)CC4)nn3C)nc2n(CCC)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ ADORA2B P29275 15/20 1.00
▸ ADORA1 P30542 8/20 1.00
▸ ADORA2A P29274 6/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1569329 0.94 ADORA2B (0.89) ADORA2BADORA1ADORA2A
SCHEMBL1780628 0.92 ADORA2B (1.00) ADORA2BADORA1ADORA2A
SCHEMBL1779738 0.90 ADORA2B (1.00) ADORA2BADORA1ADORA2A
SCHEMBL14267751 0.90 ADORA2B (1.00) ADORA2BADORA1ADORA2A
SCHEMBL1778231 0.89 ADORA2B (1.00) ADORA2BADORA1ADORA2A
SCHEMBL4759214 0.84 ADORA2B (0.75) ADORA2BADORA1ADORA2A
SCHEMBL1782025 0.80 ADORA2B (1.00) ADORA2BADORA1ADORA2A
SCHEMBL5336024 0.80 ADORA2B (0.83) ADORA2BADORA1ADORA2A
SCHEMBL14517865 0.80 ADORA2B (0.82) ADORA2BADORA1ADORA2A
SCHEMBL5334257 0.79 ADORA2B (0.82) ADORA2BADORA1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4567112-A1 RNA INHIBITOR FOR INHIBITING APOC3 GENE EXPRESSION AND USE THEREOF Kylonova (Xiamen) Biopharma Co., Ltd. (CN) 2025-06-11 — — EP claimed
CN-118215665-A Beta-lactamase inhibitor intermediate and preparation method thereof 苏州信诺维医药科技股份有限公司 2024-06-18 — — CN claimed
US-20230340237-A1 LIQUID HYDROGENATED NITRILE-BUTADIENE RUBBER, PREPARATION METHOD THEREOF AND USE THEREOF ZANNAN SCITECH CO., LTD. (CN) 2023-10-26 — — US claimed
CN-114262394-B Liquid hydrogenated nitrile rubber and preparation method and application thereof 浙江赞昇新材料有限公司 2023-08-18 — — CN claimed
CN-114262394-A Liquid hydrogenated nitrile rubber and preparation method and application thereof 浙江赞昇新材料有限公司 2022-04-01 — — CN claimed
US-20110118276-A1 METHODS OF TREATING ATHEROSCLEROSIS KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT INC 2011-05-19 — — US claimed
US-7205403-B2 8-Heteroaryl xanthine adenosine A2B receptor antagonists KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) 2007-04-17 — — US claimed
US-20060142309-A1 8-Heteroaryl xanthine adenosine A2B receptor antagonists KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. 2006-06-29 — — US claimed
US-20030207879-A1 8-Heteroaryl xanthine adenosine A2B receptor antagonists KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. 2003-11-06 — — US claimed
CN-122092907-A Photovoltaic optimizer communication method and system based on PLC — 2026-05-26 — — CN disclosed
CN-121463259-B Communication method, device and system Honor Terminal Co.,Ltd. (CN) 2026-05-26 — — CN disclosed
CN-118003730-B Weather-resistant polyolefin film and solar cell backboard prepared from same LUCKY FILM CO.,LTD. (CN) 2026-05-26 — — CN disclosed
WO-2026107232-A1 METHODS FOR PREPARING MYCELIUM SHEET OR PANEL MATERIAL FOR FURTHER PROCESSING AND/OR FINISHING ECOVATIVE LLC (US) 2026-05-21 — — WO disclosed
CN-122069488-A Intelligent iron shoe control method, intelligent iron shoe control equipment, intelligent iron shoe control medium, intelligent iron shoe product and intelligent iron shoe 株洲太昌电子信息技术股份有限公司 2026-05-19 — — CN disclosed
US-20110118276-A1 METHODS OF TREATING ATHEROSCLEROSIS KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT INC 2011-05-19 — — US disclosed
US-7335655-B2 8-heteroaryl xanthine adenosine A2B receptor antagonists KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) 2008-02-26 — — US disclosed
US-7335655-B2 8-heteroaryl xanthine adenosine A2B receptor antagonists KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) 2008-02-26 — — US disclosed
US-7335655-B2 8-heteroaryl xanthine adenosine A2B receptor antagonists KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) 2008-02-26 — — US disclosed
US-7205403-B2 8-Heteroaryl xanthine adenosine A2B receptor antagonists KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) 2007-04-17 — — US disclosed
US-20060142309-A1 8-Heteroaryl xanthine adenosine A2B receptor antagonists KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. 2006-06-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340237-A1 LIQUID HYDROGENATED NITRILE-BUTADIENE RUBBER, PREPARATION METHOD THEREOF AND USE THEREOF NOS1, NOS2, NOTUM ADORA2B 3904/4885ADORA1 3430/4885ADORA2A 4621/4885
US-20110118276-A1 METHODS OF TREATING ATHEROSCLEROSIS ADORA2B, ADORA2A, ADORA3 ADORA2B 1/4885ADORA1 4/4885ADORA2A 2/4885
US-20030207879-A1 8-Heteroaryl xanthine adenosine A2B receptor antagonists ADORA2B, ADORA2A, ADORA1 ADORA2B 1/4885ADORA1 3/4885ADORA2A 2/4885
US-20060142309-A1 8-Heteroaryl xanthine adenosine A2B receptor antagonists ADORA2B, ADORA2A, ADORA1 ADORA2B 1/4885ADORA1 3/4885ADORA2A 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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