Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 9/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.32 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259713 | 0.76 | HCRTR1 (0.39) | DRD2CYP19A1 | |
| SCHEMBL7715098 | 0.76 | ACHE (0.48) | CYP19A1 | |
| SCHEMBL7263724 | 0.76 | ACHE (0.48) | CYP19A1 | |
| SCHEMBL7715113 | 0.76 | HCRTR1 (0.39) | DRD2CYP19A1 | |
| SCHEMBL3966439 | 0.76 | PPARD (0.48) | PPARAPPARGPPARD | |
| SCHEMBL8644235 | 0.75 | PPARA (0.35) | PPARAPPARGDRD1 | |
| SCHEMBL7135478 | 0.75 | CYP19A1 (0.49) | PPARDDRD1DRD2DRD3CYP19A1 | |
| SCHEMBL8620705 | 0.72 | MTNR1A (0.34) | PPARA | |
| SCHEMBL26635080 | 0.72 | MAPT (0.67) | CYP19A1 | |
| SCHEMBL22559434 | 0.70 | CD274 (0.33) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345644-A1 | INDAZOLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |