Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636781 | 0.91 | MAPK1 (0.36) | MAPK1MAPK14 | |
| SCHEMBL8620705 | 0.84 | MTNR1A (0.34) | PPARA | |
| SCHEMBL8647745 | 0.76 | MAPK1 (0.39) | MAPK1MAPK14 | |
| SCHEMBL178121 | 0.75 | PPARA (0.38) | PPARAPPARGDRD1 | |
| SCHEMBL7715113 | 0.72 | HCRTR1 (0.39) | — | |
| SCHEMBL7259713 | 0.72 | HCRTR1 (0.39) | — | |
| SCHEMBL8617783 | 0.71 | MTNR1A (0.39) | — | |
| SCHEMBL8644997 | 0.71 | MAOA (0.37) | MAPK1 | |
| SCHEMBL3966439 | 0.70 | PPARD (0.48) | PPARAPPARG | |
| SCHEMBL7715098 | 0.70 | ACHE (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052913-A2 | LEUKOTRIENE B4 ANTAGONISTS, IN PARTICULAR 3-OXA-TETRAHYDRONAPHTHALENE-LTB4 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |