Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636781 | 0.93 | MAPK1 (0.36) | MTNR1BACHESIGMAR1KDM1AMAOA | |
| SCHEMBL8644235 | 0.84 | PPARA (0.35) | PPARA | |
| SCHEMBL7259713 | 0.83 | HCRTR1 (0.39) | ACHEKDM1AMAOAMAOB | |
| SCHEMBL7715113 | 0.83 | HCRTR1 (0.39) | ACHEKDM1AMAOAMAOB | |
| SCHEMBL7263724 | 0.81 | ACHE (0.48) | ACHEKDM1AMAOAMAOB | |
| SCHEMBL7715098 | 0.81 | ACHE (0.48) | ACHEKDM1AMAOAMAOB | |
| SCHEMBL8617783 | 0.79 | MTNR1A (0.39) | MTNR1AMTNR1BACHEKDM1AMAOA | |
| SCHEMBL8647745 | 0.75 | MAPK1 (0.39) | MTNR1AMTNR1BACHEKDM1AMAOA | |
| SCHEMBL7717534 | 0.73 | MTNR1B (0.35) | MTNR1AMTNR1BACHE | |
| SCHEMBL7717533 | 0.73 | MTNR1B (0.35) | MTNR1AMTNR1BACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052913-A2 | LEUKOTRIENE B4 ANTAGONISTS, IN PARTICULAR 3-OXA-TETRAHYDRONAPHTHALENE-LTB4 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |