SCHEMBL17827342

SCHEMBL17827342

c1ccc(-c2ccc3c(c2)c2c4oc5c(ccc6c5c5cc(-c7ccc8oc9ccccc9c8c7)ccc5n6-c5ccccc5)c4ccc2n3-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.37
PLA2G4A P47712 4/20 0.37
PLA2G10 O15496 1/20 0.34
SIRT2 Q8IXJ6 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
ALDH1A1 P00352 3/20 0.32
TSHR P16473 3/20 0.32
HPGD P15428 2/20 0.32
CHEK2 O96017 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 2/20 0.32
HSD17B10 Q99714 2/20 0.32
POLB P06746 1/20 0.32
BRCA1 P38398 1/20 0.32
KDM4E B2RXH2 3/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
ATM Q13315 1/20 0.31
MAPT P10636 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17827323 0.94 ALDH1A1 (0.35) PLA2G2APLA2G4ASIRT2SIRT1ALDH1A1
SCHEMBL16437672 0.93 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10SIRT2SIRT1
SCHEMBL19037114 0.93 TSHR (0.37) ALDH1A1TSHRHPGDSMN1; SMN2MEN1
SCHEMBL21926155 0.92 ALOX5 (0.35) PLA2G2APLA2G4APLA2G10SIRT2SIRT1
SCHEMBL16437687 0.92 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10SIRT2SIRT1
SCHEMBL20129510 0.92 TSHR (0.35) PLA2G2APLA2G4APLA2G10ALDH1A1TSHR
SCHEMBL21365546 0.92 ALDH1A1 (0.35) ALDH1A1TSHRHPGDCHEK2SMN1; SMN2
SCHEMBL17827304 0.92 MEN1 (0.34) ALDH1A1TSHRHPGDSMN1; SMN2MEN1
SCHEMBL27444650 0.91 ALDH1A1 (0.34) PLA2G2APLA2G4ASIRT2SIRT1ALDH1A1
SCHEMBL20129512 0.91 TSHR (0.35) PLA2G2APLA2G4APLA2G10ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210104680-A1 ORGANIC ELECTROLUMINESCENT ELEMINT, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2021-04-08 US disclosed
US-10910565-B2 Organic electroluminescent element, material for organic electroluminescent elements, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2021-02-02 US disclosed
US-10249826-B2 Compound, organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-04-02 US disclosed
US-9997717-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-06-12 US disclosed
US-9997717-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-06-12 US disclosed
US-20160211462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ELECTRONIC DEVICE IDEMIRSU KOSAN CO., LTD. (JP) 2016-07-21 US disclosed
US-20160211462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ELECTRONIC DEVICE IDEMIRSU KOSAN CO., LTD. (JP) 2016-07-21 US disclosed
US-20160172599-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 US disclosed
US-20160172602-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 US disclosed
US-20160172601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 US disclosed
US-20160172601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 US disclosed
US-20160172602-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10249826-B2 Compound, organic electroluminescent element and electronic device LEF1, EMC2, POU2F1 PLA2G2A 4200/4885PLA2G4A 4710/4885PLA2G10 4588/4885
US-20160172599-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE LEF1, EMC2, POU2F1 PLA2G2A 4200/4885PLA2G4A 4710/4885PLA2G10 4588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.