SCHEMBL20129510

SCHEMBL20129510

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc5c(c4)c4c6oc7ccccc7c6ccc4n5-c4ccccc4)c3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.35
PLA2G2A P14555 2/20 0.35
PLA2G4A P47712 2/20 0.35
PLA2G10 O15496 1/20 0.35
ALOX5 P09917 1/20 0.34
MAPT P10636 6/20 0.34
ALDH1A1 P00352 6/20 0.33
LMNA P02545 5/20 0.33
KDM4E B2RXH2 4/20 0.33
KMT2A Q03164 4/20 0.33
POLB P06746 3/20 0.33
HSD17B10 Q99714 3/20 0.33
MEN1 O00255 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HPGD P15428 1/20 0.33
BRCA1 P38398 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19037114 0.97 TSHR (0.37) TSHRALOX5MAPTALDH1A1LMNA
SCHEMBL20129509 0.96 TSHR (0.34) TSHRPLA2G2APLA2G4APLA2G10ALOX5
SCHEMBL20129512 0.95 TSHR (0.35) TSHRPLA2G2APLA2G4APLA2G10ALOX5
SCHEMBL16437687 0.94 PLA2G2A (0.38) TSHRPLA2G2APLA2G4APLA2G10MAPT
SCHEMBL21914665 0.94 TSHR (0.35) TSHRPLA2G2APLA2G4APLA2G10ALOX5
SCHEMBL17252975 0.93 ALOX5 (0.36) TSHRPLA2G2APLA2G4APLA2G10ALOX5
SCHEMBL24218132 0.93 TSHR (0.35) TSHRPLA2G2APLA2G4APLA2G10ALOX5
SCHEMBL21365545 0.93 TSHR (0.35) TSHRPLA2G2APLA2G4APLA2G10ALOX5
SCHEMBL21365548 0.93 TSHR (0.35) TSHRPLA2G2APLA2G4APLA2G10ALOX5
SCHEMBL19039320 0.92 ALOX5 (0.35) TSHRPLA2G2APLA2G4APLA2G10ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844269-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-12-12 US disclosed
US-11844269-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-12-12 US disclosed
US-20230242518-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-03 US disclosed
US-20230242518-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-03 US disclosed
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-25 US disclosed
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-25 US disclosed
US-11649225-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-05-16 US disclosed
US-11649225-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-05-16 US disclosed
US-20210193925-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-06-24 US disclosed
US-20210062081-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-03-04 US disclosed
US-20210036239-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-02-04 US disclosed
US-20200299274-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-09-24 US disclosed
US-10651396-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2020-05-12 US disclosed
US-20200119275-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-04-16 US disclosed
US-20180130953-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-10 US disclosed
US-20180130953-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200299274-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, SOD1, TELO2 TSHR 4361/4885PLA2G2A 3308/4885PLA2G4A 3376/4885
US-20230242518-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, SOD1, TELO2 TSHR 4361/4885PLA2G2A 3308/4885PLA2G4A 3376/4885
US-20210193925-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, TERT, ICOSLG TSHR 4119/4885PLA2G2A 3974/4885PLA2G4A 3899/4885
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, TERT, VDAC2 TSHR 4602/4885PLA2G2A 2436/4885PLA2G4A 2888/4885
US-10651396-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same AOX1, OCIAD1, OCIAD2 TSHR 4237/4885PLA2G2A 4571/4885PLA2G4A 4122/4885
US-20180130953-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME AOX1, OCIAD1, OCIAD2 TSHR 4237/4885PLA2G2A 4571/4885PLA2G4A 4122/4885
US-11649225-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, SOD1, TELO2 TSHR 4361/4885PLA2G2A 3308/4885PLA2G4A 3376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.