Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385370 | 0.91 | LMNA (0.60) | LMNACA1CA2TRPV1MAPT | |
| Ammonia Solution, Strong SCHEMBL27316369 | 0.89 | LMNA (0.59) | LMNACA1CA2TRPV1MAPT | |
| SCHEMBL21656845 | 0.87 | LMNA (0.58) | LMNACA1CA2MAPTKDM4E | |
| SCHEMBL21656479 | 0.87 | LMNA (0.58) | LMNACA1CA2MAPTKDM4E | |
| SCHEMBL2271347 | 0.86 | LMNA (0.56) | LMNACA1CA2MAPTCES2 | |
| SCHEMBL13063663 | 0.86 | LMNA (0.56) | LMNACA1CA2MAPTCES2 | |
| SCHEMBL69218 | 0.85 | CA1 (0.75) | CA1CA2MAPTKDM4EMEN1 | |
| SCHEMBL694268 | 0.85 | MAPT (0.61) | LMNACA1CA2MAPK14MAPT | |
| Methylene Chloride SCHEMBL28147089 | 0.84 | LMNA (0.55) | LMNACA1CA2MAPTCES2 | |
| SCHEMBL31575935 | 0.84 | SRD5A2 (0.65) | LMNACA1CA2TRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600696-B2 | Aromatic compounds | Xeniopro GmbH (DE) | 2026-04-14 | — | — | US | disclosed |
| US-20250346549-A2 | NOVEL AROMATIC MOLECULES | Xeniopro GmbH (DE) | 2025-11-13 | — | — | US | disclosed |
| US-20250084023-A2 | NOVEL AROMATIC MOLECULES | Xeniopro GmbH (DE) | 2025-03-13 | — | — | US | disclosed |
| US-20240140895-A1 | NOVEL AROMATIC MOLECULES | Xeniopro GmbH (DE) | 2024-05-02 | — | — | US | disclosed |
| US-20230150923-A1 | NOVEL AROMATIC COMPOUNDS | Xeniopro GmbH (DE) | 2023-05-18 | — | — | US | disclosed |
| US-11591289-B2 | Aromatic compounds | Xeniopro GmbH (DE) | 2023-02-28 | — | — | US | disclosed |
| US-20210107863-A2 | NOVEL AROMATIC COMPOUNDS | Xeniopro GmbH (DE) | 2021-04-15 | — | — | US | disclosed |
| US-20210107863-A2 | NOVEL AROMATIC COMPOUNDS | Xeniopro GmbH (DE) | 2021-04-15 | — | — | US | disclosed |
| US-20200031763-A1 | NOVEL AROMATIC COMPOUNDS | Xeniopro GmbH (DE) | 2020-01-30 | — | — | US | disclosed |
| EP-2197551-B1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | MERCK SHARP & DOHME (US) | 2016-12-28 | — | — | EP | disclosed |
| US-8455638-B2 | Soluble guanylate cyclase activators | MERCK SHARP & DOHME CORP. (US) | 2013-06-04 | — | — | US | disclosed |
| US-20110118282-A1 | Soluble Guanylate Cyclase Activators | MERCK SHARP & DOHME LLC | 2011-05-19 | — | — | US | disclosed |
| EP-2197551-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | Merck Sharp & Dohme Corp. (US) | 2010-06-23 | — | — | EP | disclosed |
| US-20090209556-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | MERCK SHARP & DOHME CORP. | 2009-08-20 | — | — | US | disclosed |
| WO-2009032249-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | MERCK & CO., INC. (US) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150923-A1 | NOVEL AROMATIC COMPOUNDS | AHR, TYR, MUSK | LMNA 3327/4885CA1 4881/4885CA2 4416/4885 |
| US-20250084023-A2 | NOVEL AROMATIC MOLECULES | AHR, TYR, MUSK | LMNA 3829/4885CA1 4876/4885CA2 4410/4885 |
| US-11591289-B2 | Aromatic compounds | AHR, TYR, MUSK | LMNA 3083/4885CA1 4882/4885CA2 4221/4885 |
| US-20110118282-A1 | Soluble Guanylate Cyclase Activators | GUCY1B1, GUCY1A2, GUCY1A1 | LMNA 532/4885CA1 4658/4885CA2 3535/4885 |
| US-20090209556-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | GUCY1B1, GUCY1A2, GUCY1A1 | LMNA 532/4885CA1 4658/4885CA2 3535/4885 |
| US-20210107863-A2 | NOVEL AROMATIC COMPOUNDS | AHR, TYR, MUSK | LMNA 3327/4885CA1 4881/4885CA2 4416/4885 |
| US-12600696-B2 | Aromatic compounds | CCR1, CCRL2, AHR | LMNA 832/4885CA1 3602/4885CA2 1477/4885 |
| US-20250346549-A2 | NOVEL AROMATIC MOLECULES | AHR, TYR, MUSK | LMNA 3829/4885CA1 4876/4885CA2 4410/4885 |
| US-20200031763-A1 | NOVEL AROMATIC COMPOUNDS | AHR, TYR, MUSK | LMNA 3327/4885CA1 4881/4885CA2 4416/4885 |
| US-20240140895-A1 | NOVEL AROMATIC MOLECULES | AHR, TYR, MUSK | LMNA 3829/4885CA1 4876/4885CA2 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.