SCHEMBL17828490

SCHEMBL17828490

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-n4c5ccccc5c5cc(-c6cccc7c6c6ccccc6n7-c6ccccc6)ccc54)c3-n3c4ccccc4c4ccccc43)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PTGER4 P35408 1/20 0.35
RXFP1 Q9HBX9 1/20 0.31
NPY5R Q15761 1/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17828496 1.00 KDM4E (0.38) KDM4EATML3MBTL1PTGER4RXFP1
SCHEMBL17828492 1.00 KDM4E (0.38) KDM4EATML3MBTL1PTGER4RXFP1
SCHEMBL20244108 0.95 KDM4E (0.34) KDM4EATML3MBTL1PTGER4
SCHEMBL17828500 0.94 KDM4E (0.38) KDM4EATML3MBTL1RXFP1MEN1
SCHEMBL17828493 0.94 KDM4E (0.38) KDM4EATML3MBTL1RXFP1MEN1
SCHEMBL17828495 0.94 KDM4E (0.38) KDM4EATML3MBTL1RXFP1MEN1
SCHEMBL17828466 0.94 KDM4E (0.39) KDM4EATML3MBTL1PTGER4RXFP1
SCHEMBL17828467 0.94 KDM4E (0.39) KDM4EATML3MBTL1PTGER4RXFP1
SCHEMBL20803527 0.93 KDM4E (0.32) KDM4EATML3MBTL1PTGER4
SCHEMBL21655554 0.93 KDM4E (0.32) KDM4EATML3MBTL1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11618722-B2 Compound, composition, organic electroluminescent element, and electronic appliance IDEMITSU KOSAN CO., LTD. (JP) 2023-04-04 US disclosed
US-11271164-B2 Compound, composition, organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD (JP) 2022-03-08 US disclosed
US-20200358000-A1 COMPOUND, COMPOSITION, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-11-12 US disclosed
EP-3276697-B1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE AND COMPOUND IDEMITSU KOSAN CO (JP) 2020-08-26 EP disclosed
US-20200035922-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-01-30 US disclosed
US-10547009-B2 Organic electroluminescent element, electronic device and compound IDEMITSU KOSAN CO., LTD. (JP) 2020-01-28 US disclosed
US-20190245152-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-08-08 US disclosed
US-20190081249-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD (JP) 2019-03-14 US disclosed
US-9997717-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-06-12 US disclosed
US-9997717-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-06-12 US disclosed
US-20180053901-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE AND COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2018-02-22 US disclosed
US-20180053901-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE AND COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2018-02-22 US disclosed
US-20160172601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 US disclosed
US-20160172601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180053901-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE AND COMPOUND LEF1, FRG1, CTNNA1 KDM4E 2467/4885ATM 2666/4885L3MBTL1 1498/4885
US-20200358000-A1 COMPOUND, COMPOSITION, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE PAX2, CXXC4, XDH KDM4E 2200/4885ATM 3205/4885L3MBTL1 2392/4885
US-11618722-B2 Compound, composition, organic electroluminescent element, and electronic appliance FGF23, SUZ12, RPL24 KDM4E 503/4885ATM 2534/4885L3MBTL1 3093/4885
US-10547009-B2 Organic electroluminescent element, electronic device and compound LEF1, FRG1, CTNNA1 KDM4E 2467/4885ATM 2666/4885L3MBTL1 1498/4885
US-11271164-B2 Compound, composition, organic electroluminescent element and electronic device PAX2, CXXC4, XDH KDM4E 2200/4885ATM 3205/4885L3MBTL1 2392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.