Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17831847 | 0.91 | AKR1C3 (0.41) | AKR1C3AKR1C2PTGS2PTGDR2KDM4E | |
| SCHEMBL17829593 | 0.83 | PTGS2 (0.37) | AKR1C3AKR1C2PTGS2PTGS1PTGDR2 | |
| SCHEMBL17829608 | 0.81 | AKR1C3 (0.42) | AKR1C3AKR1C2PTGS2PTGDR2ICMT | |
| SCHEMBL17831839 | 0.80 | ICMT (0.34) | AKR1C3AKR1C2PTGS2PTGS1KDM4E | |
| SCHEMBL17829967 | 0.79 | KDM4E (0.37) | AKR1C3AKR1C2PTGDR2KDM4EICMT | |
| SCHEMBL17818467 | 0.75 | SCN9A (0.38) | AKR1C3AKR1C2KDM4EICMTPSEN1 | |
| SCHEMBL17818469 | 0.75 | SCN9A (0.38) | AKR1C3AKR1C2KDM4EICMTPSEN1 | |
| SCHEMBL17829607 | 0.71 | MAP3K14 (0.44) | AKR1C3AKR1C2PTGDR2KDM4EPSEN1 | |
| Hydrochloric Acid SCHEMBL17818452 | 0.71 | MAPT (0.37) | AKR1C3AKR1C2KDM4EPSEN1PSEN2 | |
| SCHEMBL17818481 | 0.69 | ALDH1A1 (0.36) | AKR1C3AKR1C2GFERPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168140-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS (US) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168140-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | FOS, FOSB, YAP1 | XIAP 766/4885AKR1C3 4463/4885AKR1C2 4279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.