Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31175221 | 0.87 | SLC6A2 (0.47) | SLC6A2SLC6A4TP53MAPTALDH1A1 | |
| SCHEMBL2232118 | 0.87 | SLC6A2 (0.47) | SLC6A2SLC6A4TP53MAPTALDH1A1 | |
| SCHEMBL17830830 | 0.81 | S1PR1 (0.44) | SLC6A2SLC6A4MAPTTSHRALDH1A1 | |
| SCHEMBL19008845 | 0.80 | NR3C2 (0.41) | SLC6A2SLC6A4ALDH1A1SMN1; SMN2HTR2A | |
| SCHEMBL16373317 | 0.79 | SLC6A2 (0.54) | SLC6A2SLC6A4ALDH1A1SRCKDM4C | |
| SCHEMBL11690693 | 0.79 | SLC6A4 (0.54) | SLC6A2SLC6A4TP53MAPTALDH1A1 | |
| SCHEMBL11701093 | 0.78 | KDM4E (0.59) | SLC6A2SLC6A4TP53MAPTALDH1A1 | |
| SCHEMBL5075640 | 0.77 | KDM4E (0.52) | SLC6A2SLC6A4KDM4CNUDT1KDM4E | |
| SCHEMBL7937528 | 0.75 | ALOX5 (0.44) | TSHRALDH1A1CYP2C19SRCSMN1; SMN2 | |
| SCHEMBL13570273 | 0.74 | CES1 (0.42) | SLC6A2SLC6A4TP53MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650310-B2 | Method for the methylation of nitrogen-containing organic compounds | RHEINISCHE-WESTFÄLISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN (DE) | 2017-05-16 | — | — | US | disclosed |
| US-20160168043-A1 | METHOD FOR THE METHYLATION OF NITROGEN-CONTAINING ORGANIC COMPOUNDS | RHEINISCHE-WESTFÄLISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN (DE) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168043-A1 | METHOD FOR THE METHYLATION OF NITROGEN-CONTAINING ORGANIC COMPOUNDS | HNMT, PNMT, GNMT | SLC6A2 383/4885SLC6A4 317/4885TP53 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.