Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 4/20 | 0.39 |
| ▸ | WDR48 | Q8TAF3 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833278 | 0.90 | CYP11B2 (0.38) | USP1WDR48CYP11B2KIF11SYK | |
| SCHEMBL17829896 | 0.89 | RAD52 (0.48) | USP1WDR48SYKKMT2ARAD52 | |
| SCHEMBL17833154 | 0.85 | SYK (0.37) | USP1WDR48NR4A2SYKKMT2A | |
| SCHEMBL17833144 | 0.83 | SMN1; SMN2 (0.47) | USP1WDR48NR4A2SYKKMT2A | |
| SCHEMBL17829830 | 0.79 | RAD52 (0.51) | CYP11B2SYKKMT2ARAD52ACP1 | |
| SCHEMBL17833152 | 0.77 | ACP1 (0.42) | USP1WDR48SYKKMT2ARAD52 | |
| SCHEMBL17829910 | 0.76 | SYK (0.44) | SYKKMT2ARAD52ACP1MEN1 | |
| SCHEMBL17833277 | 0.74 | SYK (0.37) | SYKKMT2ARAD52ACP1MEN1 | |
| SCHEMBL17829897 | 0.74 | RAD52 (0.47) | KMT2ARAD52MEN1POLB | |
| SCHEMBL17833162 | 0.74 | SYK (0.39) | SYKKMT2ARAD52ACP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |