Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | HTR1D | P28221 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2071225 | 0.77 | DRD2 (0.48) | DRD2DRD3HTR1DDRD4HTR5A | |
| SCHEMBL5374896 | 0.74 | DRD2 (0.46) | DRD2DRD3HTR1DDRD4HTR5A | |
| SCHEMBL6582526 | 0.74 | PTGS2 (0.40) | DRD2DRD3HTR1DDRD4HTR5A | |
| SCHEMBL6583279 | 0.74 | MTNR1A (0.42) | DRD2DRD3HTR1DKDM4E | |
| SCHEMBL1922596 | 0.73 | KDM4E (0.55) | ARKDM4EHSD17B10MAPTCASP1 | |
| SCHEMBL6580676 | 0.72 | DRD2 (0.43) | DRD2DRD3HTR1DDRD4HTR5A | |
| SCHEMBL22488448 | 0.72 | DRD2 (0.36) | DRD2DRD3HTR1DDRD4HTR5A | |
| SCHEMBL17485148 | 0.72 | DRD2 (0.42) | DRD2DRD3HTR1DDRD4HTR5A | |
| SCHEMBL23832868 | 0.72 | DRD2 (0.50) | DRD2DRD3HTR1DDRD4HTR5A | |
| SCHEMBL23832870 | 0.72 | DRD2 (0.50) | DRD2DRD3HTR1DDRD4HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094489-A1 | PHOSPHORUS LIGANDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-06-16 | — | — | WO | disclosed |