Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Anthracene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.53 |
| ▸ | GRIN2A known ✓ | Q12879 | 1/20 | 0.43 |
| ▸ | PDE3B known ✓ | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.43 |
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 7/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HBB | P68871 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthracene SCHEMBL23302274 | 1.00 | CYP2A6 (0.58) | CYP2A6ALOX12ALDH1A1HPGDMAPT | |
| Anthracene SCHEMBL28872169 | 0.96 | CYP2A6 (0.54) | CYP2A6ALOX12ALDH1A1HPGDMAPT | |
| Anthracene SCHEMBL27696173 | 0.96 | CYP2A6 (0.54) | CYP2A6ALOX12ALDH1A1HPGDMAPT | |
| Water SCHEMBL783809 | 0.96 | ALDH1A1 (0.58) | CYP2A6ALOX12ALDH1A1HPGDMAPT | |
| Anthracene SCHEMBL5713429 | 0.95 | CYP2A6 (0.64) | CYP2A6ALOX12ALDH1A1HPGDMAPT | |
| Anthracene SCHEMBL29352043 | 0.95 | CYP2A6 (0.64) | CYP2A6ALOX12ALDH1A1HPGDMAPT | |
| Anthracene SCHEMBL2833889 | 0.95 | CYP2A6 (0.64) | CYP2A6ALOX12ALDH1A1HPGDMAPT | |
| Anthracene SCHEMBL7703 | 0.95 | CYP2A6 (0.64) | CYP2A6ALOX12ALDH1A1HPGDMAPT | |
| Anthracene SCHEMBL5945255 | 0.91 | CYP2A6 (0.58) | CYP2A6ALOX12ALDH1A1HPGDMAPT | |
| Anthracene SCHEMBL12988658 | 0.91 | CYP2A6 (0.58) | CYP2A6ALOX12ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115505100-B | Epoxy resin based on spirosilafluorene as framework, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-115505099-B | Epoxy resin containing carbazole structure, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-109776826-A | A kind of thick polyimide film and quantum carbon-based films, and preparation method thereof | 深圳丹邦科技股份有限公司 | 2019-05-21 | — | — | CN | claimed |
| US-20190051921-A1 | TWO-ELECTRON REDOX CATHOLYTE FOR REDOX FLOW BATTERIES | UCHICAGO ARGONNE, LLC | 2019-02-14 | — | — | US | claimed |
| CN-104473902-B | Light and thermal controlled nano supermolecule vesicle as well as preparation method and application thereof | 南开大学 | 2017-03-22 | — | — | CN | claimed |
| CN-104473902-A | Light and thermal controlled nano supermolecule vesicle as well as preparation method and application thereof | UNIV NANKAI | 2015-04-01 | — | — | CN | claimed |
| CN-112939758-B | Preparation method of organic optical material | 大连天源基化学有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115505100-A | Epoxy resin based on spirosilafluorene as skeleton and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-115505099-A | Epoxy resin containing carbazole structure and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-115210289-A | Polyester resin and method for producing same | 尤尼吉可株式会社 | 2022-10-18 | — | — | CN | disclosed |
| CN-112939758-A | Preparation method of organic optical material | 大连天源基化学有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-109776826-A | A kind of thick polyimide film and quantum carbon-based films, and preparation method thereof | 深圳丹邦科技股份有限公司 | 2019-05-21 | — | — | CN | disclosed |
| US-20190051921-A1 | TWO-ELECTRON REDOX CATHOLYTE FOR REDOX FLOW BATTERIES | UCHICAGO ARGONNE, LLC | 2019-02-14 | — | — | US | disclosed |
| CN-104473902-B | Light and thermal controlled nano supermolecule vesicle as well as preparation method and application thereof | 南开大学 | 2017-03-22 | — | — | CN | disclosed |
| CN-104011026-B | Insecticidal aromatic amides | 拜耳知识产权股份有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-104473902-A | Light and thermal controlled nano supermolecule vesicle as well as preparation method and application thereof | UNIV NANKAI | 2015-04-01 | — | — | CN | disclosed |
| CN-104473902-A | Light and thermal controlled nano supermolecule vesicle as well as preparation method and application thereof | UNIV NANKAI | 2015-04-01 | — | — | CN | disclosed |
| CN-104011026-A | NOVEL INSECTICIDAL AROMATIC AMIDES | BAYER IP GMBH | 2014-08-27 | — | — | CN | disclosed |
| US-20110118374-A1 | Method for Preparing a Hard Film or Coating from a Cationically Cross-Linkable/Polymerizable Composition Comprising an Iodonium Borate and Giving Off an Acceptable Odour | BLUESTAR SILICONES FRANCE SAS (FR) | 2011-05-19 | — | — | US | disclosed |
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |