Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1787340 | 0.84 | HTT (0.33) | HTTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL1783974 | 0.79 | ALDH1A1 (0.35) | HTTCYP3A4MAPTALDH1A1MEN1 | |
| SCHEMBL15330828 | 0.61 | VDR (0.47) | HTTCYP3A4MAPTVDRALDH1A1 | |
| SCHEMBL547728 | 0.60 | CYP3A4 (0.44) | CYP3A4MAPTVDRALDH1A1MEN1 | |
| SCHEMBL27196313 | 0.60 | ALDH1A1 (0.40) | CYP3A4MAPTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL26539459 | 0.60 | MEN1 (0.37) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL599510 | 0.58 | IGF1R (0.34) | CYP3A4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12080026 | 0.58 | IGF1R (0.34) | CYP3A4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28687904 | 0.57 | CYP3A4 (0.55) | CYP3A4MAPTVDRALDH1A1MEN1 | |
| SCHEMBL1799592 | 0.57 | SMN1; SMN2 (0.42) | HTTCYP3A4MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273901-B2 | Process of forming a pyrrole compound | Nanyang Technical University (SG) | 2012-09-25 | — | — | US | disclosed |
| US-20110124881-A1 | PROCESS OF FORMING A PYRROLE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124881-A1 | PROCESS OF FORMING A PYRROLE COMPOUND | OXER1, OGDH, OPRD1 | HTT 3191/4885CYP3A4 181/4885MAPT 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.