Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261593 | 0.76 | MAPT (0.40) | MEN1KMT2AMAPTTDP1HTT | |
| SCHEMBL5316660 | 0.76 | METAP1 (0.49) | MEN1KMT2AMAPTGAAPOLB | |
| SCHEMBL17844119 | 0.75 | TAAR1 (0.40) | MEN1KMT2AMAPTGAAPOLB | |
| SCHEMBL1998134 | 0.73 | POLB (0.50) | MEN1KMT2AMAPTGAATDP1 | |
| SCHEMBL17844227 | 0.71 | POLB (0.39) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL17844110 | 0.69 | MAOA (0.40) | MEN1KMT2APOLB | |
| SCHEMBL5306584 | 0.69 | NTRK1 (0.38) | — | |
| SCHEMBL17844176 | 0.69 | ADORA3 (0.35) | CYP3A4CYP2D6 | |
| SCHEMBL22809456 | 0.69 | POLB (0.69) | MEN1KMT2AMAPTGAATDP1 | |
| SCHEMBL28981214 | 0.69 | ALDH1A1 (0.65) | MEN1KMT2AMAPTGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |